Fluid Management in Critically Ill Adults: CRUSADERS Trial

We are studying whether reducing sodium and chloride in fluids helps critically ill adults have better health outcomes. This includes looking at effects on organ support needs and overall survival.

>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesInjectionInternal MedicineNephrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Glucose Viaflo Baxter
Glucose Viaflo Baxter is an IV sugar solution used to provide energy and correct low blood sugar for people who cannot eat or drink.
Nacl + Glucose Viaflo Baxter
An IV fluid that supplies water, salt, and sugar to hydrate patients and provide quick energy while helping restore body salts.
Natriumchlorid 0,9 %
Natriumchlorid 0,9% is a sterile salt solution used to replace fluids, hydrate patients, and deliver medicines into a vein.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Glucose
Glucose is a simple sugar substance that supplies quick energy and is used to raise low blood sugar levels.
Glucose Monohydrate
Glucose monohydrate is a form of sugar used to provide quick energy and to raise low blood sugar levels.
Magnesium Chloride Hexahydrate
Magnesium chloride hexahydrate is a magnesium supplement used to restore low magnesium levels and support healthy muscle and nerve function.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens
Acuolens
Addex

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Ziekenhuis Aan De Stroom
Intensive Care Unit
Antwerpen, Belgium
Ziekenhuis Aan De Stroom
Intensive Care Unit
Berchem, Belgium
Ziekenhuis Aan De Stroom
Anesthesiology, Intensive Care Unit
Merksem, Belgium
Sponsor: Universitair Ziekenhuis Antwerpen
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.