Heart Failure: Optimizing Drug Levels

We are studying how blood levels of heart failure medications affect patient health. This research may help improve treatment plans for individuals with heart failure.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Bisoprolol Fumarate
Bisoprolol Fumarate is a medicine used to treat high blood pressure and some heart conditions by slowing the heart and reducing its workload.
Carvedilol
Carvedilol is a medicine used to lower blood pressure and help treat heart failure by reducing the heart's workload.
Nebivolol
Nebivolol is a medicine used to lower high blood pressure and help protect the heart.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bisoprolol Fumarate
Bisoprolol fumarate is a substance that helps lower high blood pressure and reduce strain on the heart.
Carvedilol
Carvedilol is a substance that lowers blood pressure and heart workload by blocking heart and blood vessel receptors, used for heart failure and hypertension.
Metoprolol Succinate
Metoprolol succinate is a substance that helps lower high blood pressure and reduces strain on the heart.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acarden
Acebis
Aloneb

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Fakultni Nemocnice Ostrava
Kardiovaskulární oddělení Interní a kardiologické kliniky FN Ostrava
Hlučín, Czechia
Sponsor: Fakultni Nemocnice Ostrava
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.