Heart Failure Treatment: Carvedilol vs. Metoprolol

We are comparing two heart medications to see which one may better help patients with heart failure and reduced ejection fraction. This study involves patients who need beta-blocker treatment for their condition.

>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesOralCardiologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Carvedilol
Carvedilol is a medicine used to lower blood pressure and help treat heart failure by reducing the heart's workload.
Carvedilol Mylan
Carvedilol Mylan is a medicine used to treat high blood pressure and heart failure by helping the heart pump more effectively.
Metoprololsuccinat Al
Metoprololsuccinat Al is a medicine used to lower high blood pressure and treat certain heart conditions like chest pain and heart failure.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Carvedilol
Carvedilol is a substance that lowers blood pressure and heart workload by blocking heart and blood vessel receptors, used for heart failure and hypertension.
Metoprolol Succinate
Metoprolol succinate is a substance that helps lower high blood pressure and reduces strain on the heart.
Metoprolol Tartrate
Metoprolol tartrate is a substance that lowers heart rate and blood pressure to treat high blood pressure and certain heart conditions.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acarden
Acarden
Atram

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Odense University Hospital
Cardiology
Odense, Denmark
Sponsor: Odense University Hospital
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.