Heart Health: Apixaban vs. Warfarin Study

We are comparing two medications to see which is more effective in resolving blood clots in patients with left ventricular thrombus after a heart attack. We're also looking at safety and bleeding risks associated with each treatment.

3-6 months ≤5 visits Monitoring phase (IV)No Placebo Partially Remote Standard Medicines Oral InjectionCardiologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Eliquis

Eliquis is a medicine that helps prevent harmful blood clots and lowers the risk of stroke.

Optison

Optison is a contrast agent used during ultrasound exams to help doctors see the heart and blood flow more clearly.

Sonovue

SonoVue is a medicine given during ultrasound scans to improve image clarity and help doctors see organs and blood flow.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Apixaban

Apixaban is a substance that helps prevent harmful blood clots and lowers stroke risk in people with irregular heart rhythm.

Perflutren

Perflutren is a substance that improves heart ultrasound images by creating tiny gas-filled bubbles that enhance visualization of blood flow and chambers.

Sulfur Hexafluoride

Sulfur hexafluoride is a gas used as a temporary eye bubble to help fix detached retinas and to enhance ultrasound imaging.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abatixent

Abidalo

Aboxoma

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Danderyds Sjukhus AB

Kardiologi

Bergshamra, Sweden

Sahlgrenska University Hospital-Vaestra Goetalandsregionen

Kardiologi

Göteborg, Sweden

Karolinska University Hospital

Medicine

Huddinge, Sweden

Sponsor: Karolinska Institutet

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.