Whooping Cough
Whooping cough, or pertussis, is a highly contagious respiratory disease caused by the bacterium Bordetella pertussis, characterized by severe coughing fits that can make it hard to breathe.
Infant Immunity to Whooping Cough: Maternal Vaccination Study
We are studying how vaccines given to pregnant women affect their infants' immunity to whooping cough. Our goal is to find out what factors influence the transfer of protective antibodies from mothers to their babies.
>2 years≤5 visitsMonitoring phase (IV)No PlaceboCost ReimbursementStandard MedicinesInjectionGynecology and ObstetricsInfectious DiseasesInternal Medicine
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you a woman between 18 and 45 years old?
- Have you had a Pertussis vaccination more than 12 months ago?
- Are you currently pregnant or not pregnant?
- Is your infant 2 months old (plus or minus 1 week)?
- Does your infant weigh more than 2.5 kg at birth?
What medicines are being studied?
Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.
Act-Hib (Hib)
Act-Hib is a vaccine that helps protect infants and young children from serious infections caused by Hib bacteria.
Diftavax
Infanrix (Dtpa)
Infanrix (DTPa) is a vaccine that helps protect infants and young children against diphtheria, tetanus, and whooping cough.
Infanrix Tetra
Infanrix Tetra is a vaccine for infants and young children that protects against diphtheria, tetanus, whooping cough, polio, and Hib infections.
Pertussin
Pflügerplex Pertussis 320 H
Poliomyelitis Vaccine Bilthoven Biologicals B.V.
Poliomyelitis Vaccine Bilthoven Biologicals B.V. is a vaccine used to prevent polio.
Poliovaccine Ajv
Poliovaccine Ajv is a vaccine used to prevent polio, a virus that can cause paralysis.
Vaccin Tétanique Adsorbé Pasteur
Vaccin Tétanique Adsorbé Pasteur is a vaccine used to prevent tetanus, a serious infection that affects nerves and muscles.
Vaxelis Suspension For Injection
Vaxelis is a vaccine for infants and young children that protects against six serious infections including diphtheria, tetanus, whooping cough, polio, Hib, and hepatitis B.
What active substances are being studied?
Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.
Algeldrate
Algeldrate is a substance that neutralizes stomach acid to ease heartburn and indigestion.
Aluminium Hydroxide
Aluminium hydroxide is a substance that neutralizes stomach acid to relieve heartburn, indigestion, and acid-related discomfort.
Aluminium Phosphate
Aluminium phosphate is a substance used in vaccines to boost the body's immune response and help improve protection.
Amorphous Aluminium Hydroxyphosphate Sulphate
Amorphous aluminium hydroxyphosphate sulphate is a substance used as a vaccine adjuvant to strengthen the body's immune response to vaccination.
Bordetella Pertussis Filamentous Haemagglutinin Adsorbed On Aluminium Phosphate
Bordetella pertussis filamentous haemagglutinin adsorbed on aluminium phosphate is a substance that helps the immune system develop protection against whooping cough.
Bordetella Pertussis Fimbriae Type 2 And 3 Adsorbed On Aluminium Phosphate
Bordetella pertussis fimbriae types 2 and 3 adsorbed on aluminium phosphate helps protect against whooping cough by stimulating the immune system.
Bordetella Pertussis Pertactin Adsorbed On Aluminium Phosphate
Bordetella pertussis pertactin adsorbed on aluminium phosphate is a vaccine component that helps the body build protection against whooping cough.
Bordetella Pertussis Toxoid Adsorbed On Aluminium Phosphate
Bordetella pertussis toxoid adsorbed on aluminium phosphate is a vaccine component that prevents whooping cough by stimulating protective immunity.
Carbo Vegetabilis Trit. D 4
Carbo vegetabilis is a homeopathic substance used for bloating, gas, indigestion, and general weakness.
Cephaelis Ipecacuanha Trit. D4
Cephaelis ipecacuanha trit. D4 is a homeopathic preparation traditionally used for relief of nausea and vomiting.
Cuprum Metallicum Trit. D 4
Cuprum metallicum trit. D4 is a homeopathic substance traditionally used for muscle cramps and spasms.
Dactylopius Coccus Trit. D 1
Diphtheria Toxoid
Diphtheria toxoid is a substance that helps the immune system build protection against diphtheria.
Diphtheria Toxoid Adsorbed On Aluminium Hydroxide
Diphtheria toxoid adsorbed on aluminium hydroxide is a vaccine component that helps the body build immunity to prevent diphtheria.
Diphtheria Toxoid Adsorbed On Aluminium Phosphate
Diphtheria toxoid adsorbed on aluminium phosphate is a vaccine component that helps the body build immunity to prevent diphtheria.
Drosera Trit. D 3
Drosera trit. D3 is a homeopathic substance traditionally used for spasmodic coughs and throat irritation.
Ethanol 90%
Ethanol 90% is a substance used to kill germs and disinfect skin and surfaces.
Extracting Agent: Ethanol 70% (V/V)
Ethanol 70% is a disinfectant used to clean skin and surfaces by destroying bacteria and viruses.
Extraction Solvents: Ammonia Solution 10 % (M/M)
Glycerol 85%
Glycerol 85% is a substance that helps relieve constipation by drawing water into the bowel to soften stools.
Haemophilus Influenzae Type B Polyribosylribitol Phosphate Conjugated To Meningococcal Protein Adsorbed On Amorphous Aluminium Hydroxyphosphate Sulfate
Haemophilus influenzae type b polyribosylribitol phosphate conjugated to meningococcal protein is a vaccine substance that protects young children from serious Hib infections.
Haemophilus Type B Conjugate Vaccine (Tetanus Toxoid Conjugate)
Haemophilus influenzae type b conjugate vaccine (tetanus toxoid) protects infants and young children from serious infections like meningitis and pneumonia.
Hepatitis B Surface Antigen (Rdna) Adsorbed On Amorphous Aluminium Hydroxyphosphate Sulphate [produced In S. Cerevisiae By Rdna]
Hepatitis B surface antigen is a substance that stimulates the immune system to protect against hepatitis B infection.
Hydrated
Hyoscyamus Niger Trit. D 4
Hyoscyamus niger Trit. D4 is a homeopathic preparation traditionally used for nervous agitation, restlessness, and delirium-like symptoms.
Inactivated
Liquid Extract From Thyme Herb (Der 1:2-2,5)
Liquid extract from thyme herb is a plant-based substance traditionally used to help relieve coughs and soothe the airways.
Narcissus Pseudonarcissus (Hab 34) Trit. D 3
Narcissus pseudonarcissus (trit. D3) is a homeopathic preparation traditionally used for emotional symptoms and certain types of headaches.
Pertussis Filamentous Haemagglutinin
Pertussis filamentous haemagglutinin is a vaccine component that helps the immune system recognize and build protection against whooping cough.
Pertussis Filamentous Haemagglutinin Adsorbed On Aluminium Hydroxide
Pertussis filamentous haemagglutinin adsorbed on aluminium hydroxide is a vaccine component that trains the immune system to protect against whooping cough.
Pertussis Fimbrial Agglutinogens (Fim) 2 And 3
Pertussis Fimbrial Agglutinogens 2 and 3 are bacterial proteins used in vaccines to help the immune system protect against whooping cough.
Pertussis Pertactin
Pertactin is a pertussis protein used as a vaccine component to help prevent whooping cough.
Pertussis Pertactin Adsorbed On Aluminium Hydroxide
Pertussis pertactin adsorbed on aluminium hydroxide is a component used in whooping cough vaccines to help the body build protection.
Pertussis Toxoid
Pertussis toxoid is a substance that helps the body build protection against whooping cough.
Pertussis Toxoid Adsorbed On Aluminium Hydroxide
Pertussis toxoid adsorbed on aluminium hydroxide is a substance that helps the immune system build protection against whooping cough.
Poliovirus (Inactivated) Type 1 (Mahoney Strain)
Poliovirus (Inactivated) Type 1 (Mahoney Strain) is an inactivated virus used in vaccines to stimulate immunity and prevent polio.
Poliovirus (Inactivated) Type 1 (Mahoney Strain) Produced On Vero Cells
Poliovirus (Inactivated) Type 1 (Mahoney Strain) Produced On Vero Cells helps prevent polio by training the immune system to recognize and fight the virus.
Poliovirus (Inactivated) Type 2 (Mef-1 Strain)
Poliovirus (Inactivated) Type 2 (Mef-1 Strain) is an inactivated virus component used in vaccines to protect people from type 2 polio.
Poliovirus (Inactivated) Type 2 (Mef-1 Strain) Produced On Vero Cells
Poliovirus (inactivated) type 2 is a substance that stimulates immunity to help prevent polio caused by type 2 poliovirus.
Poliovirus (Inactivated) Type 3 (Saukett Strain)
Poliovirus (Inactivated) Type 3 (Saukett Strain) is a killed virus that helps the body develop immunity to type 3 polio.
Poliovirus (Inactivated) Type 3 (Saukett Strain) Produced On Vero Cells
Poliovirus (Inactivated) Type 3 (Saukett Strain) Produced On Vero Cells is a vaccine antigen used to stimulate immunity and prevent polio.
Poliovirus Type 1
Poliovirus Type 1 is a virus component used in vaccines to help the body build protection against polio.
Spongilla Lacustris Trit. D 3
Strain Brunhilde
Tetanus Protein
Tetanus protein is a vaccine component that stimulates the immune system to protect against tetanus infection.
Tetanus Toxoid
Tetanus toxoid is a substance that helps the body build protection against tetanus infection.
Tetanus Toxoid Adsorbed On Aluminium Hydroxide
Tetanus toxoid adsorbed on aluminium hydroxide is a substance used to prevent tetanus by stimulating protective immune responses.
Tetanus Toxoid Adsorbed On Aluminium Phosphate
Tetanus toxoid adsorbed on aluminium phosphate is a substance that protects against tetanus by stimulating the body's immune response.
Thyme Herb Dry Extract (6-10:1)
Thyme herb dry extract is a plant extract commonly used to ease coughs and support respiratory and throat comfort.
Water (1:20:70:109)
Water helps maintain hydration and supports normal bodily functions and fluid balance.
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Act-Hib
Alk (Alutard Sq)
Alk (Alutard Sq)
Alk-Depot Sq 802
Alk-Depot Sq 802
Allergovit
Allergovit
Allergovit Beh Birke + Erle + Hasel
Allergovit Beh Birke + Erle + Hasel
Allergovit Beifuß
Allergovit Beifuß
Allergovit Bi Birke
Allergovit Bi Birke
Allergovit Erle
Allergovit Erle
Allergovit Erle + Hasel
Allergovit Erle + Hasel
Allergovit G Gräser
Allergovit G Gräser
Allergovit Gg Graeser/Getreide
Allergovit Gg Graeser/Getreide
Allergovit Glaskraut
Allergovit Glaskraut
Allergovit Gr Graeser 60% + Roggen 40%
Allergovit Gr Graeser 60% + Roggen 40%
Allergovit Graeser + Beifuß + Roggen
Allergovit Graeser + Beifuß + Roggen
Allergovit Graeser + Birke + Roggen
Allergovit Graeser + Birke + Roggen
Allergovit Graeser + Roggen + Wegerich
Allergovit Graeser + Roggen + Wegerich
Allergovit Graeser 80% + Roggen 20%
Allergovit Graeser 80% + Roggen 20%
Allergovit Graeser/Getreide + Beifuß
Allergovit Graeser/Getreide + Beifuß
Allergovit Graeser/Getreide + Birke
Allergovit Graeser/Getreide + Birke
Allergovit Graeser/Getreide + Wegerich
Allergovit Graeser/Getreide + Wegerich
Allergovit Graeser+ Beifuß + Roggen + Wegerich
Allergovit Graeser+ Beifuß + Roggen + Wegerich
Allergovit Graeser+ Birke + Roggen + Wegerich
Allergovit Graeser+ Birke + Roggen + Wegerich
Allergovit Hasel
Allergovit Hasel
Allergovit Roggen
Allergovit Roggen
Allergovit Wegerich
Allergovit Wegerich
Almigástrico
Almigástrico
Aludrox
Aludrox
Alutard
Alutard
Alutard Kit D’initiation
Alutard Kit D’initiation
Alutard Sq (Zacetno Pakiranje)
Alutard Sq (Zacetno Pakiranje)
Alutard Sq Cutie Pentru Inițierea Și Creșterea Dozei
Alutard Sq Cutie Pentru Inițierea Și Creșterea Dozei
Alutard Sq Hmyzí Alergeny
Alutard Sq Hmyzí Alergeny
Alutard Sq Initial Pack
Alutard Sq Initial Pack
Alutard Sq Initial- Og Vedligeholdelsespakning venomallergen
Alutard Sq Initial- Og Vedligeholdelsespakning venomallergen
Alutard Sq Jedy Hmyzu
Alutard Sq Jedy Hmyzu
Alutard Sq Starter Pack
Alutard Sq Starter Pack
Anti Chf Vaccine
Anti Chf Vaccine
Aspecton Hustensaft
Aspecton Hustentropfen
Aspecton Junior
Bexsero
Bexsero
Boostertdap
Boostrix
Boostrix Polio
Boostrix-Ipv
Boostrixtetra
Brolion
Brolysium
Bronchiclear
Bronchiclear Tosse Mucolitico
Bronchicum T
Bronchiphyl
Bronchipret
Bronchipret Cimbru Și Iederă
Bronchipret Comp
Bronchipret Duo
Bronchipret Duo Hustenlöser
Bronchipret Expectorant
Bronchipret Forte
Bronchipret S Tymianom A Brečtanom
Bronchipret Saft
Bronchipret Saft Te
Bronchipret Te
Bronchipret Thymian Efeu
Bronchipret Thymian Efeu Saft
Bronchipret Ti
Bronchipret Ti Intens
Bronchipret Tropfen Te
Bronchipret Tymián A Břečťan
Bronchostop Bronchitis Akut
Clodivac
Covid-19 Vaccine (Inactivated, Adjuvanted)
Covid-19 Vaccine (Inactivated, Adjuvanted)
D.T. Coq
D.T. Coq
Dicarbocalm N
Dicarbocalm N
Difterie-, Tetanus-, Poliomyelitisvaccin Bilthoven Biologicals
Diftetall
Diftetall
Diphtheria, Tetanus, Poliomyelitis Vaccine Bilthoven Biologicals
Ditebooster
Ditekibooster
Dt-Reduct
Dt-Reduct
Dtap Booster
Dultavax
Dultavax
Encepur Pro Dospělé
Encepur Pro Dospělé
Engerix B
Engerix B
Epicogel
Epicogel
Expectym
Gelobronchial-Saft
Gelox
Gelox
Havrix
Havrix
Havrix Adultes
Havrix Adultes
Havrix Junior
Havrix Junior
Havrix Junior Monodose
Havrix Junior Monodose
Havrix Nourrissons Et Enfants
Havrix Nourrissons Et Enfants
Husten-Tropfen Mit Anis Und Thymian
Imovax Tetano
Infanrix
Infanrix
Infanrix Hexa
Infanrix Ipv
Infanrix Ipv
Infanrix Ipv Hib
Infanrix Ipv Hib
Infanrix Polio
Infanrix Polio
Infanrix-Polio+hib
Infanrixquinta
Infanrixtetra
Ipv Infanrix
Ipv-Boostrix
Librodyn
Maalox «χωρίσ Ζάχαρη»
Maalox «χωρίσ Ζάχαρη»
Maalox (Be Cukraus)
Maalox (Be Cukraus)
Maalox (Nesatur Cukuru)
Maalox (Nesatur Cukuru)
Maalox (Suhkruvabad)
Maalox (Suhkruvabad)
Maalox Aroma Menta
Maalox Aroma Menta
Maalox Bez Cukru S Príchuťou Citróna
Maalox Bez Cukru S Príchuťou Citróna
Maalox Maux D’estomac
Maalox Maux D’estomac
Maalox Maux D’estomac Fruits Rouges
Maalox Maux D’estomac Fruits Rouges
Maalox Maux D’estomac Sans Sucre Fruits Rouges, Édulcoré À La Saccharine Sodique, Au Sorbitol Et Au Maltitol
Maalox Maux D’estomac Sans Sucre Fruits Rouges, Édulcoré À La Saccharine Sodique, Au Sorbitol Et Au Maltitol
Maalox Maux D’estomac Sans Sucre, Édulcoré À La Saccharine Sodique, Au Sorbitol Et Au Maltitol
Maalox Maux D’estomac Sans Sucre, Édulcoré À La Saccharine Sodique, Au Sorbitol Et Au Maltitol
Maalox Premium
Maalox Premium
Maalox Stomach Ache Red Fruits
Maalox Stomach Ache Red Fruits
Makatussin Tropfen
Medithyme Cough
Melrosum
Menjugate
Menjugate
Mucofyl
Mucofyl Forte
Mucolion
Mucoplant Kvapky Proti Kašľu
Mucopret
Neisvac-C
Novo-Helisen Depot
Novo-Helisen Depot
Novo-Helisen Depot Milbenpräparate
Novo-Helisen Depot Milbenpräparate
Novo-Helisen Dermatophagoides Farinae
Novo-Helisen Dermatophagoides Farinae
Novo-Helisen Dermatophagoides Farinae + Dermatophagoides Pteronyssinus
Novo-Helisen Dermatophagoides Farinae + Dermatophagoides Pteronyssinus
Novo-Helisen Dermatophagoides Pteronyssinus
Novo-Helisen Dermatophagoides Pteronyssinus
Pentavac
Pentaxim
Pepsamar
Pepsamar
Pertusinas, Vaikams
Picovax
Polioboostrix
Polioinfanrix
Poliomyelitisvaccin Bilthoven Biologicals
Poliomyelitisvaccin Bilthoven Biologicals
Poliomyelitisvaccin Multidose Bilthoven Biologicals
Poliomyelitisvaccin Multidose Bilthoven Biologicals
Pulmonest
Revaxis
Revaxis
Sallevia
Syrop Tymiankowy Złozony
Szczepionka Przeciw Blonicy, Adsorbowana Instytut Biotechnologii Surowic I Szczepionek Biomed Spółka Akcyjna
Szczepionka Przeciw Błonicy, Adsorbowana O Zmniejszonej Zawartości Antygenu Instytut Biotechnologii Surowic I Szczepionek Biomed Spółka Akcyjna
Szczepionka Tezcowa Adsorbowana (T)
Td-Immun
Td-Pur
Td-Pur
Td-Pur Für Erwachsene Und Heranwachsende
Td-Pur Für Erwachsene Und Heranwachsende
Tdap Szczepionka
Tdap-Immun
Tdapbooster
Tetana
Tetana Pro
Tetanusvaccine "ajv"
Tetavax
Tetavax
Tetravac
Tetraxim
Thymian
Thymian Hustensaft
Thymiverlan
Timiāna Un Efejas Bionorica
Timifit
Timijan In Slez Bronchostop
Toularynx Thym
Tribaccine
Tussamag
Tussamag Zuckerfrei
Tussiflorin Thymian
Vacteta
Vacteta
Vaqta Felnőttek Számára Készült
Vaqta Felnőttek Számára Készült
Vaqta Junior Gyermekek És Serdülokorúak Számára Készült
Vaqta Junior Gyermekek És Serdülokorúak Számára Készült
Vaxelis
Vaxelis
Veropol
Алмагел
Алмагел
Бронхикум
Бронхипрет
Бронхипрет (Bronchipret)
Бронхипрет Ти
Бронхостоп
Бустрикс
Бустрикс Полио
Дифтет
Дифтет
Дифтеткок Без Кон Серв Ант
Дифтеткок Без Кон Серв Ант
Инфанрикс-Ipv+hib
Тетадиф
Тетадиф
Тетатокс
Тетатокс
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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CHU Saint Pierre
Pediatrics
Saint-Gilles, Belgium
Sponsor: Universite Libre de Bruxelles
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.