Klinefelter Syndrome: Testosterone Treatment in Puberty

We are studying how testosterone replacement therapy affects boys with Klinefelter syndrome during puberty. This includes looking at changes in body composition, growth, and overall development.

>2 years Monitoring phase (IV)Standard MedicinesEndocrinologyUrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Androgel

AndroGel is a prescription skin gel that replaces testosterone in men with low levels to help reduce symptoms like fatigue and low sex drive.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Testosterone

Testosterone is a hormone substance used to replace low male sex hormones and help restore energy, libido, and muscle strength.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Androtop

Itnogen

Testarzon

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Aalborg University Hospital

Department of Pediatrics

Aalborg, Denmark

Aarhus Universitetshospital

Department of Paediatrics and Adolescent Medicine

Århus, Denmark

Rigshospitalet

Department of Growth and Reproduction

Copenhagen, Denmark

Sponsor: Rigshospitalet

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.