Metastatic Renal Cell Carcinoma: Immunotherapy and Tumor Treatment Study

We are studying how surgery and radiation affect survival and tumor growth in patients with metastatic renal cell carcinoma receiving immunotherapy. This trial aims to improve treatment strategies and quality of life for these patients.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Axitinib Eg
Axitinib Eg is a cancer medicine used to treat advanced kidney cancer.
Cabozantinib Ipsen
Cabozantinib Ipsen is a cancer medicine used to treat certain advanced kidney, liver, and thyroid cancers.
Lenvima
Lenvima is a cancer medicine used to treat certain types of thyroid, liver, and kidney cancers.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Axitinib
Axitinib is a substance that helps slow the growth of certain cancers, mainly advanced kidney cancer.
Cabozantinib
Cabozantinib is a substance used to treat certain advanced cancers by blocking signals that help tumors grow and spread.
Ipilimumab
Ipilimumab is a substance that helps the immune system attack cancer by blocking a protein that keeps immune cells from working.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aksitinib Alpha-Medical
Aksitinib Sandoz
Aksitinib Teva

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Azienda Universitaria Ospedaliera Consorziale Policlinico Bari
Oncologia Medica
Altamura, Italy
Azienda Unita' Sanitaria Locale Toscana Sud Est
Oncologia Medica
Arezzo, Italy
Ospedale Cardinal Massaia
Oncologia
Asti, Italy

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.