Migraine Prevention: Comparing Common Medications

We are studying how well different medications prevent migraines in primary care patients. This trial aims to find out which treatment reduces migraine days and improves quality of life.

≤3 months Monitoring phase (IV)No Placebo Standard Medicines OralInternal MedicineNeurology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Amitriptyline Bb

Amitriptyline Bb is a medicine used to treat depression and certain types of long-term nerve pain.

Flunarizine Cf

Flunarizine Cf is a medicine used to prevent migraines and treat dizziness.

Propranolol

Propranolol is a medicine used to lower blood pressure and heart rate and to treat tremors, migraines, and anxiety.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Amitriptyline

Amitriptyline is a substance that treats depression and is also used for certain chronic pain conditions and migraine prevention.

Amitriptyline Hydrochloride

Amitriptyline hydrochloride is a substance used to treat depression and some types of long-term nerve pain.

Flunarizine

Flunarizine is a substance used to prevent migraines and to reduce dizziness from balance disorders.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adepril

Adt

Amineurin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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CAP Canet de Mar

ecalvo.mn.ics@gencat.cat

Canet de Mar, Spain

CAP El Castell

Castelldefels, Spain

CAP Santa Coloma de Queralt

Cervera, Spain

Sponsor: Institut Universitari D Investigacio En Atencion Primaria Jordi Gol

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.