Neurocritical Patients: Inhalation vs. Intravenous Sedation

We are studying whether inhalation sedation with isoflurane is more effective and safer than conventional intravenous sedation for patients in critical neurological care. This trial will help us understand the best sedation methods for these patients.

Monitoring phase (IV)No PlaceboStandard MedicinesInjectionInternal MedicineNeurologyOtolaryngology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Isoflurane Piramal
Isoflurane Piramal is an inhaled anesthetic used to help patients sleep during surgery.
Midazolam
Midazolam is a medicine used to calm and sedate people for medical procedures and to help control serious seizures.
Propofol
Propofol is a fast-acting anesthetic medicine used to put people to sleep for surgeries and other medical procedures.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Isoflurane
Isoflurane is a substance used to induce and maintain general anesthesia during surgeries.
Midazolam
Midazolam is a substance that produces sedation and reduces anxiety, often used to calm patients before procedures or help control seizures.
Propofol
Propofol is a substance that causes quick loss of consciousness and provides short-term sedation for surgeries and medical procedures.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aerrane
Anesia
Anesia Baxter

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hospital Universitari De Girona Doctor Josep Trueta
Intensive Care Unit
Girona, Spain
Sponsor: Hospital Universitari De Girona Doctor Josep Trueta
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.