Non-transfusion Dependent Beta-Thalassemia
Non-transfusion dependent beta-thalassemia is a genetic blood disorder that affects hemoglobin production, leading to mild to moderate anemia without the need for regular blood transfusions.
Non-Transfusion-Dependent Thalassemia: Luspatercept Treatment
We are studying whether luspatercept can improve brain oxygen levels and blood flow in patients with non-transfusion-dependent thalassemia. The trial also looks at its effects on cognitive function and heart health.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Do you have beta-thalassemia (a blood disorder)?
- Are you currently pregnant or breastfeeding?
- Have you had more than 5 blood transfusions in the last 24 weeks?
- Do you have severe kidney problems (like a kidney function test showing less than 30 mL/min)?
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
Loading map...
Amsterdam UMC
Clinical Hemtalogy
Abcoude, Netherlands
Amsterdam UMC
Clinical Hematology
Amstelveen, Netherlands
Sponsor: Amsterdam UMC
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.