Opioid Dependency Treatment: Suboxone vs. Methadone

We are comparing the effectiveness of Suboxone and methadone in reducing opioid misuse for patients with chronic pain. The study also looks at how these treatments affect pain relief, well-being, and cognitive function.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Suboxone
Suboxone is a medicine used to treat opioid addiction by reducing cravings and withdrawal symptoms.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Buprenorphine
Buprenorphine is a substance that eases opioid withdrawal and reduces cravings to help people recover from opioid dependence.
Methadone Hydrochloride
Methadone hydrochloride is a long-acting opioid used to treat opioid dependence and relieve severe chronic pain.
Naloxone
Naloxone is a substance that quickly reverses opioid overdoses, restoring breathing and consciousness.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acimaphin
Acinorphin
Addnok

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Radboud universitair medisch centrum / RADBOUDUMC
Psychiatry
Nijmegen, Netherlands
Sponsor: Stichting Radboud universitair medisch centrum
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.