Osteoporosis: Zoledronate After Denosumab

We are studying if zoledronate can prevent bone loss in patients with osteoporosis who have stopped denosumab treatment. This trial also looks at how this treatment affects muscle strength and insulin sensitivity.

>2 yearsConfirmation phase (III)Monitoring phase (IV)Standard MedicinesInjectionInternal MedicineOtolaryngology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Zoledronate Eg
Zoledronate Eg is a medicine used to strengthen bones and help prevent fractures in conditions like osteoporosis and certain cancers.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Sodium Chloride Solution 0.9%
Sodium chloride 0.9% is a sterile salt solution used to replace fluids and electrolytes, hydrate patients, and clean wounds or body cavities.
Zoledronic Acid
Zoledronic acid is a substance that helps prevent bone loss and reduce bone complications from cancer.
Zoledronic Acid Monohydrate
Zoledronic acid monohydrate is a bisphosphonate that helps prevent bone loss and reduce bone complications from osteoporosis and cancer.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acid Zoledronic Accord
Acid Zoledronic Fresenius Kabi
Acide Zoledronique Altan

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Aalborg University Hospital
Dept of Endocrinology
Aalborg, Denmark
Aarhus University Hospital
Dept. of Endocrinology and Internal Medicine
Århus, Denmark
Sponsor: Aarhus University Hospital
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.