Ovarian and Breast Cancer: zAvatar Test Study

We are exploring whether the zAvatar test can help guide treatment decisions for patients with relapsed ovarian cancer and metastatic breast cancer. This study compares outcomes from the zAvatar test approach to standard care.

Monitoring phase (IV)No Placebo Standard Medicines Oral InjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Capecitabine

Capecitabine is a chemotherapy medicine used to treat certain cancers, including breast and colon cancer.

Carboplatin

Carboplatin is a chemotherapy medicine used to treat various types of cancer.

Etoposide

Etoposide is a chemotherapy medicine used to treat various types of cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Abemaciclib

Abemaciclib is a substance that slows growth of certain breast cancer cells by blocking proteins that help them divide.

Alpelisib

Alpelisib is a substance that targets a cancer growth pathway to treat certain breast cancers with specific gene mutations.

Atezolizumab

Atezolizumab is a substance that helps the immune system recognize and attack certain cancers by blocking a protein called PD-L1.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abutrax

Aedon

Afultrant

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Unidade Local De Saude Lisboa Ocidental E.P.E.

Medical oncology

Algés, Portugal

Champalimaud Clinical Centre

Breast

Belém, Portugal

Champalimaud Clinical Centre

Gynecology

Belém, Portugal

Sponsor: Rita Fior

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.