Ovarian Stimulation for Poor Responders: CFA vs. Modified Natural Cycles

We are comparing a single cycle of a new medication with multiple natural cycles in women who may not respond well to fertility treatments. The goal is to see which method leads to better quality embryos and higher chances of pregnancy.

3-6 months ≤5 visits Monitoring phase (IV)No Placebo Investigational Medicines InjectionEndocrinologyGynecology and Obstetrics

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ganirelix

Ganirelix is a medicine used during fertility treatments to prevent early ovulation and help eggs mature properly for procedures like IVF.

Orgalutran

Orgalutran is a medicine used in fertility treatments to prevent early ovulation and help control egg development.

Ovitrelle

Ovitrelle is a medicine used in fertility treatments to trigger ovulation and help release mature eggs for conception or IVF.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Choriogonadotropin Alfa

Choriogonadotropin alfa is a substance that triggers ovulation and supports fertility treatments by mimicking a natural reproductive hormone.

Corifollitropin Alfa

Corifollitropin alfa is a long-acting fertility hormone used to stimulate ovarian follicle growth during assisted reproductive treatments.

Follitropin Beta

Follitropin beta is a hormone substance used to stimulate the ovaries to produce eggs during fertility treatments.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Elonva

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Astarté

Fyremadel

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Universitair Ziekenhuis Gent

Reproductive Medicine

Ledeberg, Belgium

Sponsor: Universitair Ziekenhuis Gent

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.