Pneumococcal Vaccine Response: Age and HIV Impact

We are studying how age and HIV infection affect the immune response to pneumococcal vaccination. This research aims to improve vaccine effectiveness for different populations.

6-12 months 6-10 visits Confirmation phase (III)Monitoring phase (IV)No Placebo Cost Reimbursement Standard Medicines InjectionInfectious DiseasesInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Pneumovax 23

Pneumovax 23 is a vaccine that helps protect adults and some children from pneumonia and other serious infections caused by pneumococcal bacteria.

Prevenar 20

Prevenar 20 is a vaccine that helps prevent pneumonia and other serious infections caused by certain bacteria.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Pneumococcal Polysaccharide Serotype 1

Pneumococcal polysaccharide serotype 1 is a vaccine component that helps the immune system prevent infections caused by pneumococcus serotype 1.

Pneumococcal Polysaccharide Serotype 1 Conjugated To Crm197 Adsorbed On Aluminium Phosphate

Pneumococcal polysaccharide serotype 1 conjugated to CRM197 adsorbed on aluminium phosphate is a vaccine component that helps protect against pneumococcal serotype 1 infections.

Pneumococcal Polysaccharide Serotype 10a

Pneumococcal polysaccharide serotype 10A is a vaccine ingredient that helps the immune system protect against pneumonia-causing bacteria of serotype 10A.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Pneumovax

Pneumovax®

Prevenar 13

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Leids Universitair Medisch Centrum (LUMC)

Infectious Diseases

Leiden, Netherlands

Sponsor: Academisch Ziekenhuis Leiden

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.