Postoperative Pain Management After Cardiac Surgery: NSAIDs Study

We are investigating whether nonsteroidal anti-inflammatory drugs can help reduce pain after cardiac surgery. This study will also look at how these medications affect recovery and overall quality of life.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Nefopam
Nefopam is a medicine used to relieve moderate pain, often after surgery or injury.
Paracetamol
Paracetamol relieves pain and reduces fever for conditions like headaches, muscle aches, and colds.
Tramadol
Tramadol is a pain reliever used to treat moderate to moderately severe pain.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Ketoprofen
Ketoprofen is a substance that reduces pain, inflammation, and fever.
Nefopam
Nefopam is a substance that relieves moderate to severe pain by acting on the central nervous system.
Nefopam Hydrochloride
Nefopam hydrochloride is a pain-relieving substance used to treat moderate acute pain by acting on the central nervous system.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

4-In-One Flu Relief
6 Years Plus Paracetamol Boots
Abacat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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CHU De Rouen
réanimation en chirurgie cardiaque
Bois-Guillaume, France
Centre Hospitalier Universitaire De Caen Normandie
Anesthésiologie et médecine de soins intensifs
Caen, France
Centre Hospitalier Universitaire Amiens Picardie
Anesthésie et Réanimation
Colomiers, France

Sponsor: Centre Hospitalier Universitaire Amiens Picardie
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.