Primary IgA Nephropathy: Long-Term Study of Iptacopan

We are evaluating the long-term safety and tolerability of iptacopan in adults with primary IgA nephropathy. This study follows participants who have completed an earlier trial to see how well the treatment works over time.

>2 years 11-15 visits Confirmation phase (III)Monitoring phase (IV)Post-Trial Drug Access Cost Reimbursement Partially Remote Investigational Medicines OralInternal MedicineNephrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Combi

Movicol Plain

Movicol Plain is a medicine used to relieve constipation by softening stools and making bowel movements easier.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Fluprednidene Acetate

Fluprednidene acetate is a corticosteroid substance that reduces skin inflammation and itching.

Iptacopan

Iptacopan is a substance that blocks part of the immune complement system to prevent red blood cell destruction in certain rare blood disorders.

Losartan

Losartan is a substance that helps lower high blood pressure.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Ace Inhibitors

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Accusol 35

Accusol 35 Kalium

Accusol 35 Potassium

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Leuven

4300: Nefrology

Heverlee, Belgium

Algemeen Ziekenhuis Delta

4301: Nefrology

Rumbeke, Belgium

Antwerp University Hospital

4302: Nefrology

Wilrijk, Belgium

Sponsor: Novartis Pharma AG

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.