Prostate Cancer Treatment: Docetaxel vs. Androgen Receptor-targeted Agents

We are studying whether docetaxel is more effective than abiraterone or enzalutamide for men with advanced prostate cancer and specific negative prognostic factors. This research aims to improve treatment outcomes and quality of life.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Abiraterone
Abiraterone is a medicine used to treat prostate cancer by lowering male hormones that can make the cancer grow.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Abiraterone
Abiraterone is a substance that reduces testosterone production to help manage advanced prostate cancer.
Abiraterone Acetate
Abiraterone acetate is a substance that lowers the body's male hormones to slow the growth of prostate cancer.
Docetaxel
Docetaxel is a chemotherapy substance used to treat various cancers by stopping cancer cells from dividing.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abaxan
Abibam®
Abinone

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Azienda Sanitaria Locale Cn2 Alba-Bra
Oncologia
Alba, Italy
Azienda Ospedaliero Universitaria Delle Marche
Medicna Interna- SOD Clinica Oncologica
Ancona, Italy
Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico
Oncologia Medica
Bologna, Italy

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.