Prucalopride for Refractory Gastro-Esophageal Reflux Disease

We are testing a new medication for patients with GERD who still have symptoms despite taking standard treatments. The goal is to see if this drug can improve their reflux symptoms.

≤3 months ≤5 visits Monitoring phase (IV)Post-Trial Drug Access Cost Reimbursement Partially Remote Standard Medicines OralGastroenterologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Prucalopride

Prucalopride is a medicine used to treat chronic constipation by helping the intestines move and increasing bowel movements.

Prucalopride Prolepha

Prucalopride Prolepha is a medicine used to treat chronic constipation by helping increase and make bowel movements more regular.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Prucalopride

Prucalopride is a substance that helps stimulate bowel movements to relieve chronic constipation.

Prucalopride Succinate

Prucalopride succinate is a substance that stimulates the bowel to relieve chronic constipation.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Absken

Colopridix

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Brussel

Gastroenterology

Ganshoren, Belgium

UZ Leuven

Gastroenterology and Hepatology

Heverlee, Belgium

Antwerp University Hospital

Gastroenterology and Hepatology

Wilrijk, Belgium

Sponsor: UZ Leuven

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.