Rheumatoid Arthritis: Adalimumab Tapering Study

We are investigating the lowest effective dose of adalimumab for patients with rheumatoid arthritis in remission. The study also looks at how well patients tolerate the treatment and the development of antibodies.

1-2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesInjectionInternal MedicineRheumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Humira
Humira is a medicine that reduces inflammation by calming the immune system to treat autoimmune conditions such as arthritis and Crohn’s disease.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Adalimumab
Adalimumab is a biologic that blocks a key inflammatory protein (TNF) to reduce inflammation in autoimmune conditions like rheumatoid arthritis and Crohn's disease.
Infliximab
Infliximab is a substance that reduces inflammation by blocking a protein called TNF and is used for autoimmune conditions like rheumatoid arthritis and Crohn's.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Amgevita
Amsparity
Hefiya

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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CLINIQUE DE L INFIRMERIE PROTESTANTE
Rhumatologie
Caluire-et-Cuire, France
Centre Hospitalier Universitaire Reims
Rhumatologie
Cormontreuil, France
Centre Hospitalier Departemental Vendee
Rhumatologie
La Roche-sur-Yon, France
Sponsor: Centre Hospitalier Universitaire De Saint Etienne
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.