Rheumatoid Arthritis: Rituximab Tapering Strategies

We are studying different ways to reduce rituximab doses in patients with rheumatoid arthritis. The goal is to find the best method to lower disease impact and activity.

>2 years 6-10 visits Monitoring phase (IV)Post-Trial Drug Access No Placebo Cost Reimbursement Standard Medicines InjectionInternal MedicineRheumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Mabthera

Mabthera is a medicine used to treat certain blood cancers and some autoimmune diseases by targeting problematic immune cells.

Rixathon

Rixathon is a medicine used to treat certain blood cancers and autoimmune diseases by targeting and reducing specific immune cells.

Ruxience

Ruxience is a medicine used to treat certain blood cancers and some autoimmune diseases.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Rituximab

Rituximab is a substance that targets and reduces B cells, a type of white blood cell, to treat some blood cancers and autoimmune conditions.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Blitzima

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Azorg

Rheumatology

Aalst, Belgium

UZ Brussel

Rheumatology

Ganshoren, Belgium

Reumacentrum Genk

Rheumatology

Genk, Belgium

Sponsor: UZ Leuven

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.