S-ketamine for Severe Acute Brain Injury

We are studying whether S-ketamine can help patients with severe acute brain injuries who have ongoing brain activity issues. The trial also looks at the safety of this treatment and its effects on recovery over six months.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Esketamine Hydrochloride
Esketamine hydrochloride is a fast-acting substance used to treat severe depression when other treatments haven’t worked.
Sodium Chloride
Sodium chloride is a substance used to replace salts and fluids in the body and to clean or irrigate wounds and nasal passages.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Rigshospitalet
Department of Neurosurgery
Copenhagen, Denmark
Sponsor: Rigshospitalet
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.