Schizophrenia: Intensified Treatment Study

We are investigating whether a six-week intensified medication plan helps individuals with schizophrenia who didn't respond to their first treatment. The study looks at changes in symptoms, functioning, and overall well-being compared to standard care.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Amisulpride Eg
Amisulpride Eg is a medicine used to treat schizophrenia and other mental health conditions that affect thinking and behavior.
Clozapine
Clozapine is a medicine used to treat severe schizophrenia that hasn't responded to other drugs and to reduce risk of suicide.
Fluanxol
Fluanxol is a medicine used to treat schizophrenia and other psychotic disorders.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Amisulpride
Amisulpride is a substance used to treat schizophrenia and other psychotic conditions by helping balance brain chemicals involved in thinking and mood.
Aripiprazole
Aripiprazole is a substance that helps control symptoms of schizophrenia, bipolar disorder, and some forms of depression.
Asenapine
Asenapine is a substance that treats schizophrenia and bipolar disorder by reducing psychotic symptoms and stabilizing mood.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adovia
Agavan
Aktiprol

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medizinische Universitaet Innsbruck
Universitätsklinik für Psychiatrie I
Innsbruck, Austria
Universitätsklinik für Psychiatrie und Psychotherapie Bielefeld
Psychiatrie und Psychotherapy
Bielefeld, Germany
University Hospital Frankfurt am Main
Department of Psychiatry, Psychosomatic Medicine and Psychotherapy
Frankfurt am Main, Germany

Sponsor: Universitair Medisch Centrum Utrecht
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.