Sepsis Treatment: Meropenem vs. Piperacillin/Tazobactam

We are comparing two antibiotics to see which one may help critically ill adults with sepsis survive better and improve their health outcomes.

6-12 monthsMonitoring phase (IV)No PlaceboStandard MedicinesInjectionInfectious DiseasesInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Meropenem
Meropenem is a strong antibiotic used to treat serious bacterial infections, often in hospital settings.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Linezolid
Linezolid is an antibiotic substance used to treat serious Gram-positive bacterial infections, including resistant strains.
Meropenem
Meropenem is an antibiotic substance used to treat serious bacterial infections, including severe or hospital-acquired infections.
Meropenem Anhydrous
Meropenem anhydrous is an antibiotic substance used to treat severe bacterial infections by killing a wide range of bacteria.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Agenor
Agenorem
Archifar

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Aalborg University Hospital
Department of Intensive Care
Aalborg, Denmark
Region Midtjylland
Department of Intensive Care, East
Århus, Denmark
Region Midtjylland
Department of Intensive Care, North
Århus, Denmark
Sponsor: Rigshospitalet
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.