Turner Syndrome: Oral vs. Transdermal Estrogen

We are studying whether oral and transdermal estrogen treatments provide similar benefits for women with Turner Syndrome. This research may help tailor hormone therapy to individual needs.

≤3 months Monitoring phase (IV)No Placebo Standard Medicines OralEndocrinologyGynecology and Obstetrics

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Divigel

Divigel is a topical estrogen gel used to relieve menopause symptoms such as hot flashes and vaginal dryness.

Estrofem

Estrofem is a hormone replacement medicine used to relieve menopause symptoms like hot flashes and help protect bone health in women after menopause.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Anhydrous Estradiol

Anhydrous estradiol is a form of the hormone estrogen used to replace low estrogen levels and relieve menopausal symptoms.

Estradiol

Estradiol is a hormone used to replace low estrogen and relieve menopausal symptoms.

Estradiol Hemihydrate

Estradiol hemihydrate is a form of the female hormone estrogen used to replace low estrogen and relieve menopausal symptoms.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Activelle

Activelle Low

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Department of Endocrinology and Internal Medicine, Aarhus University Hospital

Endocrinology and Internal Medicine

Århus, Denmark

Sponsor: Region Midtjylland

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.