Type 2 Diabetes: SGLT-2 Inhibitors and Heart Health

We are studying how SGLT-2 inhibitors may improve heart function and nerve health in people with type 2 diabetes. This research aims to understand the connection between these medications and heart regulation.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Canagliflozin Teva
Canagliflozin Teva is a medicine used to lower blood sugar in adults with type 2 diabetes.
Dapagliflozin
Dapagliflozin is a medicine that lowers blood sugar in adults with type 2 diabetes and can help protect the heart and kidneys.
Empaglifozin
Empaglifozin is a medicine that helps lower blood sugar in adults with type 2 diabetes and can reduce the risk of heart-related problems.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Canagliflozin
Canagliflozin is a substance that helps lower blood sugar in people with type 2 diabetes by causing the kidneys to remove excess sugar.
Dapagliflozin
Dapagliflozin is a substance that helps lower blood sugar in people with type 2 diabetes by causing the kidneys to remove excess glucose in urine.
Empagliflozin
Empagliflozin is a substance that helps lower blood sugar in people with type 2 diabetes by increasing sugar removal in the urine.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adiabin
Adimuplan
Altuxerin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Ospedale Isola Tiberina Gemelli Isola
UOS Endrocrinologia e Diabetologia
Rome, Italy
Sponsor: Universita Cattolica Del Sacro Cuore
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.