VAXXAIR TRIAL: Comparing Nasal and Injectable Flu Vaccines

We are studying how well a nasal flu vaccine works compared to an injectable one in building immunity. This research aims to find out which method produces a stronger immune response in the body.

>2 years 6-10 visits Monitoring phase (IV)Cost Reimbursement Investigational Medicines InjectionInfectious DiseasesPulmonology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Fluenz

Fluenz is a nasal spray vaccine that helps prevent seasonal flu in children and adolescents.

Vaxigrip

Vaxigrip is a vaccine used to protect people against seasonal flu.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

A/Cambodia/E0826360/2020 (H3n2) - Like Strain (A/Tasmania/503/2020, Ivr-221)

A/Cambodia/E0826360/2020 (H3N2)-like strain is an influenza A virus used to develop and test seasonal flu vaccines.

A/Victoria/2570/2019 (H1n1)pdm09-Like Strain (A/Victoria/2570/2019, Ivr-215)

A/Victoria/2570/2019 (H1N1)pdm09-like strain is an influenza strain used in vaccines to stimulate immunity against H1N1 seasonal flu.

B/Austria/1359417/2021 Like Strain-(B/Michigan/01/2021, Wild Type)

B/Austria/1359417/2021-like is an influenza B virus strain used in vaccines to help prevent infection from similar viruses.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Fluenz

Influenza vaccine

Inactivated

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Efluelda

Efluelda Stungulyf

Efluelda Tetra

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Gentofte Hospital

Department of Pulmonary Medicine

Charlottenlund, Denmark

Sponsor: Gentofte Hospital

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.