Whipple's Procedure: Antibiotic Treatment Comparison

We are studying whether pre-emptive antibiotics can lower the risk of infections after Whipple's surgery compared to standard antibiotic treatment. This trial aims to improve recovery outcomes for patients undergoing this procedure.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cefuroxim Hikma
Cefuroxim Hikma is an antibiotic medicine used to treat various bacterial infections, such as respiratory, ear, skin, and urinary tract infections.
Cefuroxime
Cefuroxime is an antibiotic medicine used to treat common bacterial infections of the lungs, sinuses, skin, and urinary tract.
Metronidazol Fresenius
Metronidazol Fresenius is an antibiotic medicine used to treat certain bacterial and parasitic infections.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cefuroxime
Cefuroxime is an antibiotic substance used to treat common bacterial infections like those of the respiratory tract, urinary tract, and skin.
Cefuroxime Sodium
Cefuroxime sodium is an antibiotic substance used to treat bacterial infections such as respiratory, urinary tract, and skin infections.
Metronidazole
Metronidazole is a substance that treats certain bacterial and parasitic infections, especially anaerobic and intestinal infections.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acea
Anaerobex
Anaptivan

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Jeroen Bosch Ziekenhuis
Department of Surgery
's-Hertogenbosch, Netherlands
Amsterdam UMC Stichting
Departement of Surgery
Amstelveen, Netherlands
Stichting OLVG
Department of Surgery
Amsterdam, Netherlands

Sponsor: Academisch Ziekenhuis Leiden
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.