Whooping Cough Vaccine: Tdap-IPV Study

We are studying whether a booster shot of the Tdap-IPV vaccine helps prevent colonization by whooping cough bacteria in healthy adults after exposure. This research aims to improve vaccination strategies against whooping cough.

≤3 monthsMonitoring phase (IV)No PlaceboCost ReimbursementPartially RemoteStandard MedicinesOralInjectionInfectious Diseases

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Azitromycine Teva
Azitromycine Teva is an antibiotic medicine used to treat various bacterial infections like respiratory, ear, and skin infections.
Polio-Salk Mérieux
Polio-Salk Mérieux is a vaccine used to prevent polio, a disease that can cause paralysis.
Repevax
Repevax is a vaccine that protects against diphtheria, tetanus, whooping cough, and polio.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Algeldrate
Algeldrate is a substance that neutralizes stomach acid to ease heartburn and indigestion.
Aluminium Hydroxide
Aluminium hydroxide is a substance that neutralizes stomach acid to relieve heartburn, indigestion, and acid-related discomfort.
Aluminium Phosphate
Aluminium phosphate is a substance used in vaccines to boost the body's immune response and help improve protection.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adacel
Adacel Polio
Alk (Alutard Sq)

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Radboud universitair medisch centrum / RADBOUDUMC
Laboratory Medical Immunology
Nijmegen, Netherlands
Sponsor: Stichting Radboud University Medical Center
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.