X-linked Adrenoleukodystrophy
X-linked Adrenoleukodystrophy (X-ALD) is a rare genetic disorder that affects the nervous system and adrenal glands, leading to progressive neurological decline and adrenal insufficiency.
X-ALD: Pramipexole for Leg Symptoms
We are investigating whether pramipexole can help reduce restless leg symptoms in women with X-linked Adrenoleukodystrophy. This study aims to improve their sleep and walking performance.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Restless Legs Syndrome
Restless Legs Syndrome (RLS) is a common neurological condition that causes an uncontrollable urge to move your legs, often accompanied by uncomfortable sensations, especially during periods of rest.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you a woman?
- Are you at least 18 years old?
- Are you currently pregnant?
- Do you have a diagnosis of Alcoholic Liver Disease (ALD)?
- Have you had any major psychiatric disorders that need treatment?
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Calmolan
Calmolan Retard
Derinik
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Amsterdam UMC Stichting
Neurology
Abcoude, Netherlands
Sponsor: Amsterdam UMC Stichting
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.