Search Clinical Trials in the European Union

Duration
Visits
Phase
Injection
Benefits
Drugs
Locations
Clinical Specialty
1041-1060 of 2,120 trials

Membranous Nephropathy: Personalized Rituximab Treatment Study

We are exploring whether an AI-driven personalized treatment plan for membranous nephropathy is more effective than standard rituximab treatment. This study aims to improve patient outcomes and remission rates.

Acute GlomerulonephritisMembranous Nephropathy6-12 monthsConfirmation phase (III)Monitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesNephrology

GEN1047 for Solid Tumors - First in Human Trial

We are testing a new treatment called GEN1047 for people with malignant solid tumors. The study aims to find the safest dose and evaluate how well it works against cancer.

Malignant Solid Tumors6-12 monthsSafety phase (I)Efficacy phase (II)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementOncology

Hidradenitis Suppurativa: Lutikizumab Study

We are evaluating the effectiveness and safety of lutikizumab for treating moderate to severe hidradenitis suppurativa in adults and adolescents. This study compares lutikizumab to a placebo to see how well it works.

Hidradenitis Suppurativa1-2 yearsConfirmation phase (III)>20 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementDermatology

Axial Spondyloarthritis and Psoriatic Arthritis: Ixekizumab Study

We are examining how ixekizumab affects inflammation in patients with axial spondyloarthritis and psoriatic arthritis. This study uses whole-body MRI to measure changes in joints and entheses.

Psoriatic ArthritisAxial Spondyloarthritis>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesOrthopedics and TraumatologyRheumatology

Stroke Treatment: Anesthesia vs. Sedation

We are comparing general anesthesia to sedation with high-flow nasal cannula for patients undergoing treatment for acute ischemic stroke. Our goal is to see which method leads to better recovery and fewer complications.

Acute Ischemic Stroke>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesNeurologyOtolaryngology

Whipple's Procedure: Antibiotic Treatment Comparison

We are studying whether pre-emptive antibiotics can lower the risk of infections after Whipple's surgery compared to standard antibiotic treatment. This trial aims to improve recovery outcomes for patients undergoing this procedure.

Pancreatoduodenectomy with High Risk for Contaminated Bile>2 yearsConfirmation phase (III)Monitoring phase (IV)No PlaceboStandard MedicinesGastroenterologyInfectious Diseases

Colorectal Cancer: SGM-101 Imaging Study

We are testing a new imaging agent to help surgeons detect brain metastases from colorectal cancer during surgery. This study aims to see how well it works and its safety for patients.

Brain Metastases1-2 yearsEfficacy phase (II)≤5 visitsNo PlaceboInvestigational MedicinesNeurologyOncology

Rectal Cancer Surgery: SGM-101 Imaging Study

We are testing a new imaging agent, SGM-101, to see if it helps surgeons better detect rectal cancer during surgery. This study is for patients with locally advanced or recurrent rectal cancer who are undergoing curative surgery.

Rectal Cancer>2 yearsEfficacy phase (II)≤5 visitsNo PlaceboInvestigational MedicinesGastroenterologyOncology

Rectal Polyps: SGM-101 Fluorescent Tracer Study

We are investigating a new imaging technique using SGM-101 to help identify cancerous and non-cancerous tissues in patients with rectal polyps. This study aims to improve how doctors detect early-stage rectal cancer.

Early Rectal Cancer1-2 yearsEfficacy phase (II)≤5 visitsNo PlaceboInvestigational MedicinesPartially RemoteGastroenterologyOncology

Locally Advanced Rectal Cancer: Dostarlimab and Radiotherapy

We are studying a new treatment combining dostarlimab and short-course radiotherapy for patients with specific types of rectal cancer. The goal is to see if this approach helps improve treatment success and quality of life.

Locally Advanced Rectal Cancer with Genetic Deficiencies>2 yearsEfficacy phase (II)No PlaceboInvestigational MedicinesGastroenterologyOncology

Metastatic Non-Small-Cell Lung Cancer: LN-145 Treatment Study

We are investigating whether LN-145, a type of immune cell therapy, is safe and effective for patients with metastatic non-small-cell lung cancer. The study will assess how well it works in shrinking tumors and improving patient outcomes.

Metastatic Non-Small-Cell Lung CancerEfficacy phase (II)No PlaceboInvestigational MedicinesCost ReimbursementOncology

Knee Surgery Pain Relief: Oral vs. IV Medications

We are comparing the effectiveness of oral pain relief to intravenous options for patients after knee arthroscopy. This study aims to see which method better manages pain and affects recovery.

Postoperative Pain Relief1-2 yearsMonitoring phase (IV)Standard MedicinesOrthopedics and TraumatologyOtolaryngology

Post-Stroke Spasticity: Dry Needling vs. Botulinum Toxin

We are exploring how Dry Needling and Botulinum Toxin type A affect spasticity in the lower limbs of stroke survivors. The study will also look at safety, muscle function, and quality of life.

Spasticity after Stroke3-6 monthsEfficacy phase (II)16-20 visitsNo PlaceboStandard MedicinesNeurologyOrthopedics and Traumatology

Tezepelumab for Progressive Pulmonary Fibrosis

We are studying whether Tezepelumab can help reduce symptoms and improve lung function in people with progressive pulmonary fibrosis and high eosinophil levels. This trial compares the medication to a placebo to evaluate its effectiveness.

Interstitial Pulmonary Fibrosis1-2 yearsEfficacy phase (II)6-10 visitsPost-Trial Drug AccessStandard MedicinesPartially RemotePulmonology

Brain Radionecrosis: Bevacizumab vs. Placebo

We are studying whether adding bevacizumab to standard corticosteroid therapy helps improve symptoms and reduce steroid use in patients with brain radionecrosis after radiotherapy. This trial also looks at safety and quality of life.

Brain Metastases and Radionecrosis>2 yearsConfirmation phase (III)≤5 visitsInvestigational MedicinesNeurologyOncology

Pain Relief After Esophageal Procedure: Levobupivacaine Study

We are testing a local anesthetic to see if it helps reduce pain after endoscopic submucosal dissection for esophageal lesions. The study will also look at its safety and impact on recovery time.

Visible Esophageal Lesions (Pre-cancerous)>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesGastroenterologyInternal MedicineOtolaryngology

Advanced Melanoma: Relatlimab with Nivolumab Study

We are investigating whether combining Relatlimab with Nivolumab helps people with untreated advanced melanoma live longer and have better outcomes than Nivolumab alone.

Metastatic Melanoma1-2 yearsEfficacy phase (II)Confirmation phase (III)No PlaceboStandard MedicinesPartially RemoteOncology

Angelman Syndrome: GTX-102 Treatment Study

We are investigating the long-term safety and effectiveness of GTX-102 for individuals with Angelman Syndrome. The study looks at improvements in cognitive function, communication, and motor skills.

Angelman's SyndromeConfirmation phase (III)No PlaceboInvestigational MedicinesNeurology

Cirrhosis Treatment: Efinopegdutide Study

We are testing efinopegdutide in adults with compensated cirrhosis caused by metabolic dysfunction. The study aims to see if it can reduce liver fat and improve liver health compared to a placebo.

Non-alcoholic Steatohepatitis6-12 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesEndocrinologyHepatology

Cytoreductive Surgery: Albumin and Ringer Lactate Study

We are testing whether a combination of 20% albumin and Ringer Lactate improves recovery after surgery for patients with peritoneal carcinosis. This study compares it to Ringer Lactate alone to see which is more effective.

Peritoneal Carcinomatosis>2 yearsConfirmation phase (III)No PlaceboInvestigational MedicinesPartially RemoteGastroenterologyGynecology and ObstetricsInternal MedicineOncology