Search Clinical Trials in the European Union

Duration
Visits
Phase
Injection
Benefits
Drugs
Locations
Clinical Specialty
1941-1960 of 2,120 trials

Patritumab Deruxtecan for Pediatric Solid Tumors

We are studying a new treatment for children with relapsed or refractory solid tumors to see if it is safe and effective. This trial aims to understand how well it works compared to existing options.

HepatoblastomaRhabdomyosarcoma>2 yearsSafety phase (I)Efficacy phase (II)Investigational MedicinesCost ReimbursementOncologyPediatrics

Indocyanine Green in Gynecological Cancer Surgery

We are testing a dye to improve blood flow assessment during surgery for patients with recurrent gynecological cancer. This study aims to see if it helps reduce complications and improve surgical outcomes.

Gynecological CancersPelvic Exenteration>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesGynecology and ObstetricsOncology

Durvalumab for Non-Surgical Non-Small Cell Lung Cancer

We are studying the safety and effectiveness of the immunotherapy durvalumab followed by radiation in patients with early stage or locally advanced non-small cell lung cancer. This trial aims to find out if this treatment approach can help those who cannot have surgery.

Non-Small Cell Lung Cancer1-2 yearsSafety phase (I)Efficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesOncology

Antibiotics in Children with Brain Tumors

We are studying how different antibiotics move into the cerebrospinal fluid of children with malignant brain tumors. This research may help improve treatment for infections in these patients.

Brain Tumors>2 yearsSafety phase (I)No PlaceboStandard MedicinesInfectious DiseasesOncologyPediatrics

Levosimendan for Faster Recovery from Ventilation

We are studying whether levosimendan can help critically ill patients wean off invasive ventilation more quickly. The trial also examines patient experiences and healthcare needs during recovery.

Difficulty Stopping Mechanical Ventilation≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesCardiologyPulmonology

Advanced Non-Small Cell Lung Cancer: Cemiplimab Treatment Study

We are investigating whether treatment decisions based on blood tests for tumor DNA improve outcomes for patients with advanced non-small cell lung cancer. This includes testing Cemiplimab alone or with chemotherapy.

Non-small Cell Lung Cancer>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesOncology

Kidney Transplant: Mannitol vs. Normal Saline

We are studying whether mannitol can help improve kidney transplant outcomes by reducing delayed graft function and early rejections. This trial involves both kidney donors and recipients.

End-Stage Renal Disease>2 yearsMonitoring phase (IV)Standard MedicinesNephrologyUrology

Triple-Negative Breast Cancer: Dato-DXd Treatment

We are studying a new drug for patients with triple-negative breast cancer and brain metastases to see if it can help shrink tumors and improve survival. The trial also examines safety and quality of life for participants.

Triple Negative Breast Cancer>2 yearsEfficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesNeurologyOncology

Peyronie's Disease: FAPI-PET/CT and FDG-PET/CT Scans

We are investigating whether special imaging scans can detect inflammation and active tissue changes in men with acute Peyronie's Disease. This may help improve diagnosis and treatment options.

Peyronie's Disease6-12 monthsMonitoring phase (IV)No PlaceboInvestigational MedicinesCost ReimbursementOtolaryngologyUrology

Kidney Protection: Cilastatin vs. Thiosulfate

We are comparing cilastatin and thiosulfate to see which better protects kidneys during surgery with chemotherapy for cancer patients. This study aims to reduce kidney damage after the procedure.

Acute Kidney Injury>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesInternal MedicineNephrologyOncology

Malaria Prevention: Atovaquone-Proguanil Study

We are testing a weekly dose of atovaquone-proguanil to see if it can prevent malaria in healthy volunteers. The study also looks at the safety of the medication and how it behaves in the body.

Malaria6-12 monthsEfficacy phase (II)16-20 visitsInvestigational MedicinesInfectious Diseases

Chronic Lymphocytic Leukemia: BGB-16673 Treatment Study

We are studying a new treatment called BGB-16673 for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma who have previously used other therapies. The goal is to see if it works better than current treatment options.

Chronic Lymphocytic Leukemia and Small Cell Lymphocytic Lymphoma>2 yearsConfirmation phase (III)No PlaceboInvestigational MedicinesHematologyOncology

BCG Vaccine for Radiologically Isolated Syndrome (RIS)

We are studying whether the BCG vaccine can help reduce new brain lesions in people diagnosed with Radiologically Isolated Syndrome. The trial also looks at the safety of the vaccine and other brain changes over time.

Radiologically Isolated Syndrome>2 yearsEfficacy phase (II)≤5 visitsNo PlaceboStandard MedicinesInfectious DiseasesNeurology

Knee Osteoarthritis: Study of 4P004 Treatment

We are investigating whether the treatment 4P004 can reduce pain and improve function in people with knee synovitis and osteoarthritis. Participants will receive either the treatment or a placebo to assess its effectiveness and safety.

Knee Synovitis and Osteoarthritis≤3 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesPartially RemoteOrthopedics and TraumatologyRheumatology

Virus-Specific T-Cell Therapy for Resistant Viral Infections Post-Stem Cell Transplant

We are studying the safety of using specially selected T-cells to treat young patients with viral infections like Adenovirus and Cytomegalovirus after a stem cell transplant. The trial also aims to see how well this treatment controls symptoms related to these infections.

Graft Infection1-2 yearsSafety phase (I)No PlaceboHematologyInfectious Diseases

Bladder Cancer: New Treatment Combination Study

We are investigating a new treatment combining chemotherapy and immunotherapy with radiotherapy for patients with non-metastatic muscle invasive bladder cancer. The goal is to see if this approach improves survival and quality of life after surgery.

Non-Metastatic Muscle Invasive Bladder Cancer1-2 yearsEfficacy phase (II)16-20 visitsNo PlaceboStandard MedicinesOncologyUrology

Pancreatic Cancer: Nabpaclitaxel Chemotherapy Study

We are studying a new combination of chemotherapy treatments for patients with pancreatic cancer that has spread to the abdominal lining. The goal is to see if this approach can help shrink tumors and improve survival.

Pancreatic Cancer with Peritoneal MetastasesEfficacy phase (II)No PlaceboStandard MedicinesGastroenterologyOncology

Myasthenia Gravis: Rituximab Treatment Study

We are studying whether rituximab can help improve symptoms and quality of life for patients with generalized AChR-antibody positive Myasthenia Gravis. The trial will also assess its safety and impact on other treatments.

Generalized Myasthenia Gravis6-12 monthsConfirmation phase (III)Standard MedicinesNeurologyRheumatology

Cardiac Arrest: Landiolol Treatment Study

We are testing whether adding landiolol can help patients who have had a cardiac arrest regain a stable heartbeat faster. This study will also look at overall survival and safety outcomes.

Cardiac Arrest and Ventricular Fibrillation6-12 monthsEfficacy phase (II)6-10 visitsStandard MedicinesPartially RemoteCardiologyInternal Medicine

Atrial Fibrillation Prevention: Landiolol Hydrochloride

We are studying whether Landiolol hydrochloride can help prevent atrial fibrillation in patients undergoing heart surgery. This trial looks at how often this condition occurs in the days following the surgery.

Normal Heart RhythmNormal Ejection FractionBeta-blocker Use≤3 monthsConfirmation phase (III)6-10 visitsStandard MedicinesCardiologyInternal Medicine