Search Clinical Trials in the European Union

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1681-1694 of 1,694 trials

Chronic Dialysis: Patiromer for Potassium Management

We are studying whether patiromer can help patients on chronic dialysis eat more potassium-rich foods safely. This trial looks at its impact on health-related quality of life and dietary restrictions.

End Stage Kidney DiseaseConfirmation phase (III)Investigational MedicinesNephrology

Colonoscopy Prep: Mannitol vs. Plenvu®

We are studying whether mannitol is as effective and acceptable as Plenvu® for bowel preparation before a colonoscopy. This trial aims to ensure patient comfort and safety during the procedure.

Colonoscopy3-6 monthsConfirmation phase (III)≤5 visitsNo PlaceboStandard MedicinesPartially RemoteGastroenterology

Covert Brain Infarction: Antiplatelet and Lipid-Lowering Treatments

We are studying whether adding antiplatelet and cholesterol-lowering medications can help patients with covert brain infarctions reduce serious health risks. This trial will also assess the impact on cognitive health and overall mortality.

Covert Brain Infarct>2 yearsConfirmation phase (III)No PlaceboStandard MedicinesPartially RemoteCardiologyNeurology

Leriglitazone: Drug Interaction Study

We are studying how the new drug leriglitazone interacts with other medications and food in healthy men. This research may help us understand its safety and effectiveness when taken with certain drugs or after a high-fat meal.

AdrenoleukodystrophySafety phase (I)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesInternal MedicineNeurology

Metastatic Non-Small Cell Lung Cancer: BMS-986504 Treatment Study

We are studying a new drug, BMS-986504, combined with pembrolizumab and chemotherapy for patients with metastatic non-small cell lung cancer and a specific genetic deletion. The goal is to see if this combination improves survival compared to a placebo treatment.

Metastatic Non-Small Cell Lung CancerEfficacy phase (II)Confirmation phase (III)Investigational MedicinesCost ReimbursementOncology

Migraine Study: Effects of Cilostazol

We are investigating how cilostazol affects migraine headaches in men and women without aura. The study looks at potential differences in response based on sex.

Migraine6-12 monthsSafety phase (I)Efficacy phase (II)≤5 visitsStandard MedicinesCost ReimbursementPartially RemoteNeurology

Cangrelor for Acute Ischemic Stroke Treatment

We are studying the safety and effectiveness of an intravenous medication called Cangrelor for patients with acute ischemic stroke and significant carotid artery blockage. This trial aims to see if it helps improve blood flow during emergency stenting procedures.

Ischemic Stroke with Large Artery Occlusion>2 yearsEfficacy phase (II)≤5 visitsNo PlaceboStandard MedicinesPartially RemoteCardiologyNeurology

Vormatrigine for Adults with Epilepsy

We are studying the safety and tolerability of vormatrigine in adults with focal or generalized tonic-clonic seizures. We also aim to explore its effects on seizure frequency and overall patient experience.

Focal Epilepsy and Tonic-Clonic EpilepsyConfirmation phase (III)11-15 visitsPost-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteNeurology

Zoldonrasib for RAS G12D-Mutant Non-Small Cell Lung Cancer

We are studying the effects of zoldonrasib in patients with RAS G12D-mutant non-small cell lung cancer who have been previously treated. The goal is to see how well it works and how safe it is compared to existing treatments.

Non-small Cell Lung Cancer>2 yearsEfficacy phase (II)No PlaceboInvestigational MedicinesCost ReimbursementOncologyPulmonology

Type 2 Diabetes: SGLT-2 Inhibitors and Heart Health

We are studying how SGLT-2 inhibitors may improve heart function and nerve health in people with type 2 diabetes. This research aims to understand the connection between these medications and heart regulation.

Type 2 DiabetesMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesCardiologyEndocrinologyNeurology

Lung Cancer: Zipalertinib with Chemotherapy

We are studying whether adding zipalertinib to chemotherapy helps lung cancer patients with uncommon EGFR mutations after surgery. This trial compares the new treatment to a placebo combined with standard chemotherapy.

Non-small Cell Lung Cancer (NSCLC)Confirmation phase (III)Post-Trial Drug AccessInvestigational MedicinesCost ReimbursementOncology

Bile Acid Diarrhea: Atorvastatin Treatment Study

We are investigating whether atorvastatin can help reduce bile acid production and improve symptoms in patients with moderate to severe bile acid diarrhea. The study will also look at various health markers and safety.

Bile Acid Diarrhoea3-6 monthsConfirmation phase (III)Monitoring phase (IV)6-10 visitsStandard MedicinesCost ReimbursementGastroenterology

Cabergoline for Episodic Migraine Relief

We are studying whether cabergoline can help reduce the frequency and severity of migraines in people with episodic migraine. Participants will receive either cabergoline or a placebo to compare effects.

Episodic Migraine6-12 monthsConfirmation phase (III)≤5 visitsPost-Trial Drug AccessStandard MedicinesPartially RemoteNeurology

Kidney Protection: Semaglutide and Finerenone in CKD

We are studying how semaglutide and finerenone may help protect the kidneys in people with chronic kidney disease. This includes patients with and without diabetes to explore their effects and mechanisms.

Chronic Kidney Disease6-12 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteEndocrinologyNephrology