Search Clinical Trials in the European Union

Duration
Visits
Monitoring phase (IV)
Intake methods
Benefits
Drugs
Locations
Clinical Specialty
281-300 of 552 trials

Colorectal Polypectomy: Anticoagulation Study

We are investigating whether continuing blood-thinning medication during polypectomy is safe for patients. The goal is to see if it helps reduce the risk of blood clots during the procedure.

Patients on Anticoagulants for Colonoscopy>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesPartially RemoteGastroenterologyHematology

Cataract Surgery: Preoperative NSAIDs Study

We are comparing how different medication regimens affect inflammation after cataract surgery. This study aims to find the best approach to improve recovery for patients.

Cataract1-2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesOphthalmology

Multiple Sclerosis: Siponimod Therapy Study

We are exploring how siponimod affects inflammation in patients with active secondary progressive multiple sclerosis. The study aims to understand its impact on disease progression and patient health over time.

Progressive Multiple Sclerosis>2 yearsMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesNeurology

Chronic Low Back Pain: Tricortin 1000 Study

We are testing Tricortin 1000 to see if it helps relieve pain better than a placebo and an existing treatment for chronic low back pain. This study aims to improve pain management for those experiencing acute flare-ups.

Low Back Pain≤3 monthsMonitoring phase (IV)≤5 visitsInvestigational MedicinesInternal MedicineOrthopedics and Traumatology

Major Depressive Disorder: Liposom Forte with Citalopram

We are studying whether Liposom Forte can enhance and speed up the response to citalopram in elderly patients with Major Depressive Disorder. The trial also looks at the safety of this treatment.

Major Depression3-6 monthsMonitoring phase (IV)6-10 visitsStandard MedicinesPsychiatry

Psoriatic Arthritis: Guselkumab for Enthesitis

We are studying whether Guselkumab can help reduce inflammation in patients with psoriatic arthritis who have not received prior treatments. This trial focuses on those with ultrasound-confirmed enthesitis.

Psoriatic Arthritis1-2 yearsMonitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesInfectious DiseasesRheumatology

ANCA Vasculitis: Stopping Immunosuppressive Therapy

We are studying whether stopping immunosuppressive therapy helps patients with ANCA vasculitis and end-stage renal disease avoid serious health issues compared to continuing treatment.

End-stage Renal DiseaseANCA Vasculitis>2 yearsConfirmation phase (III)Monitoring phase (IV)11-15 visitsNo PlaceboStandard MedicinesNephrologyRheumatology

Botox for Inability to Belch

We are studying whether Botox injections into the upper esophageal sphincter can help people who struggle to belch. This trial compares the effects of Botox with a placebo to assess symptom improvement.

Esophageal Disorders>2 yearsMonitoring phase (IV)≤5 visitsStandard MedicinesCost ReimbursementPartially RemoteGastroenterologyOtolaryngology

Wheezing in Young Children: Oral Prednisolone Study

We are investigating whether oral prednisolone helps children under 2 years old with wheezing caused by rhinovirus. This study aims to find out if it improves their breathing and overall comfort.

Rhinovirus-induced WheezingMonitoring phase (IV)Standard MedicinesPediatricsPulmonology

Bladder Cancer: Neoadjuvant Chemotherapy Study

We are testing whether bladder instillation of neoadjuvant chemotherapy can help prevent recurrence in patients with non-muscle-invasive bladder cancer. This study compares it to standard treatment to assess effectiveness and side effects.

Non-muscle invasive bladder cancer>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesOncologyUrology

Colon Cancer: HIPEC with Mitomycin-C Study

We are investigating whether adding a special chemotherapy during surgery helps prevent cancer recurrence in patients with colon cancer that has spread to the abdomen. This study compares outcomes for those receiving this treatment versus standard care.

Peritoneal Metastases of Colorectal Cancer>2 yearsMonitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesOncology

Pain Relief for First-Degree Perineal Tears: Emla Cream vs. Injection

We are comparing a topical cream to an injection for pain relief in women with first-degree perineal tears after childbirth. The goal is to see which method provides better comfort during and after the repair.

First-Degree Perineal Laceration6-12 monthsMonitoring phase (IV)No PlaceboStandard MedicinesGynecology and Obstetrics

Vaginal Progesterone for IVF: Improving Live Birth Rates

We are studying whether vaginal progesterone helps women achieve live births after frozen embryo transfer. The trial compares outcomes between those receiving progesterone and those who do not.

Infertility≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesEndocrinologyGynecology and Obstetrics

Shingrix Vaccine: Safety in Psoriasis and Psoriatic Arthritis

We are studying the safety and immune response of the Shingrix vaccine in patients with psoriasis or psoriatic arthritis. Our goal is to see how the vaccine affects disease activity and to monitor any side effects.

Psoriatic ArthritisPsoriasis Vulgaris>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesPartially RemoteAllergologyDermatology

Primary Adrenal Insufficiency: Plenadren vs. Cortisone

We are investigating how treatment with Plenadren affects quality of life compared to cortisone in individuals aged 16-80 newly diagnosed with primary adrenal insufficiency.

Primary Adrenal Insufficiency>2 yearsConfirmation phase (III)Monitoring phase (IV)6-10 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesPartially RemoteEndocrinology

Recurrent Lower Respiratory Tract Infections: Buccalin Tablets

We are studying Buccalin tablets to see if they can help prevent recurrent lower respiratory tract infections. This trial aims to gather more information on their safety and effectiveness.

Recurrent Lower Respiratory Tract InfectionsMonitoring phase (IV)16-20 visitsStandard MedicinesInternal MedicinePulmonology

Sepsis Treatment: New Antibiotic Dosing Strategy

We are testing a new way to dose beta-lactam antibiotics for critically ill patients with sepsis. The goal is to see if this improves their recovery in the ICU.

Sepsis1-2 yearsConfirmation phase (III)Monitoring phase (IV)No PlaceboStandard MedicinesInfectious DiseasesInternal MedicinePulmonology

Juvenile Idiopathic Arthritis: MOVE-JIA Trial

We are comparing two treatment withdrawal strategies for children and adolescents with Juvenile Idiopathic Arthritis in remission. The goal is to see which method better prevents disease flares compared to ongoing stable treatment.

Juvenile Idiopathic Arthritis>2 yearsMonitoring phase (IV)6-10 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesInternal MedicineRheumatology

Frozen Shoulder Treatment: Corticosteroid Injection with Nerve Block

We are studying whether a corticosteroid injection combined with a nerve block provides better pain relief and shoulder function than an injection with a placebo. This trial aims to help improve treatment strategies for patients with Frozen Shoulder.

Frozen ShoulderAdhesive Capsulitis1-2 yearsMonitoring phase (IV)≤5 visitsStandard MedicinesOrthopedics and Traumatology

Cryptogenic Stroke: STOP Trial on Blood Thinners

We are studying whether stopping blood thinners is as safe as continuing them for young people after a stroke with no known cause. This research may help understand the best approach to prevent future heart problems.

Stroke>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesPartially RemoteCardiologyNeurology