Search Clinical Trials in the European Union

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541-552 of 552 trials

Atrial Fibrillation: Amiodarone Administration Study

We are comparing intravenous and enteral amiodarone in critically ill patients with new-onset atrial fibrillation. The goal is to see which method is more effective in restoring normal heart rhythm and improving overall health.

Atrial Fibrillation with Rapid Ventricular Response≤3 monthsMonitoring phase (IV)No PlaceboInvestigational MedicinesCardiologyInternal Medicine

Lactose Intolerance Diagnosis: LacTEST for Children

We are studying the LacTEST to see if it accurately diagnoses lactose intolerance in children aged 5 to 11. The trial will also check the test's safety and whether a shorter urine collection time is effective.

Lactose Intolerance≤3 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesPartially RemoteGastroenterologyPediatrics

Chikungunya Vaccine: Effectiveness and Safety Study

We are evaluating how well the chikungunya vaccine works in preventing severe disease and hospitalizations in at-risk populations. This study aims to understand the vaccine's real-life impact on health outcomes.

Chikungunya1-2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesInfectious Diseases

Type 2 Diabetes: SGLT-2 Inhibitors and Heart Health

We are studying how SGLT-2 inhibitors may improve heart function and nerve health in people with type 2 diabetes. This research aims to understand the connection between these medications and heart regulation.

Type 2 DiabetesMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesCardiologyEndocrinologyNeurology

RSV Immunization Study: Nirsevimab for Infants

We are studying how the nirsevimab immunization affects infants' immune responses to RSV infections. This research aims to understand the role of age, weight, and maternal antibodies in developing immunity.

Healthy Infants1-2 yearsMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesInfectious DiseasesPulmonology

Bile Acid Diarrhea: Atorvastatin Treatment Study

We are investigating whether atorvastatin can help reduce bile acid production and improve symptoms in patients with moderate to severe bile acid diarrhea. The study will also look at various health markers and safety.

Bile Acid Diarrhoea3-6 monthsConfirmation phase (III)Monitoring phase (IV)6-10 visitsStandard MedicinesCost ReimbursementGastroenterology

Open-Heart Surgery: Parasternal Block for Pain Relief

We are studying whether a special nerve block helps reduce pain and opioid use in patients recovering from open-heart surgery. This trial aims to improve recovery experiences for these patients.

Postoperative Pain Management>2 yearsConfirmation phase (III)Monitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesPartially RemoteCardiologyInternal MedicineOtolaryngology

Chronic Constipation: Lecicarbon® Treatment Study

We are evaluating the safety and tolerability of long-term treatment with Lecicarbon® for people with chronic constipation. This study aims to understand how well patients can manage this treatment over time.

Chronic Constipation1-2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesGastroenterology

Kidney Protection: Semaglutide and Finerenone in CKD

We are studying how semaglutide and finerenone may help protect the kidneys in people with chronic kidney disease. This includes patients with and without diabetes to explore their effects and mechanisms.

Chronic Kidney Disease6-12 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteEndocrinologyNephrology

Influenza Vaccine Study: Seqirus H5N8

We are investigating how well the Seqirus H5N8 influenza vaccine works in adults who have been previously vaccinated and those who have never received an H5 vaccine. The study aims to assess immune responses and safety in both groups.

H5N1 Influenza Immunization≤3 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesInfectious Diseases

Metastatic Breast Cancer: Trastuzumab-Deruxtecan Study

We are studying how body weight influences the effects and side effects of trastuzumab-deruxtecan in patients with metastatic breast cancer. This research may help improve treatment strategies for different body types.

Metastatic Breast Cancer>2 yearsMonitoring phase (IV)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesPartially RemoteInternal MedicineOncology

COVID-19 Vaccine Study: BIMERVAX® LP.8.1

We are evaluating the safety and immune response of the BIMERVAX® LP.8.1 vaccine against COVID-19 variants. This study aims to understand how well it works in generating antibodies to fight the virus.

COVID-19≤3 monthsMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesInfectious Diseases