We are studying how androgen deprivation therapy affects the expression of a specific protein in metastatic prostate cancer. This research may help us understand treatment responses and disease progression better.
We are testing a new therapy using engineered immune cells for people with active B-cell driven autoimmune diseases. The study aims to assess safety and effectiveness in conditions like lupus and scleroderma.
We are studying whether deferoxamine can improve how people with type 1 diabetes react to low oxygen levels. This trial will help us understand its potential benefits in managing diabetes.
We are testing a new treatment, MK-5684, for people with certain solid tumors to see if it helps them live longer without disease progression. The study also evaluates its safety and effectiveness compared to standard care.
We are studying whether rezafungin can effectively treat chronic pulmonary aspergillosis in adults with few treatment options. The trial will assess both the effectiveness and safety of this medication.
We are studying whether melatonin or low-dose quetiapine can improve sleep in adolescents with psychiatric disorders and insomnia. We’ll also look at how these treatments affect overall well-being and daily functioning.
We are studying a new test to help doctors determine the best third-line therapy for patients with metastatic colorectal cancer. The goal is to see if this test provides accurate and reliable information for treatment decisions.
We are studying a new treatment combining V940 with pembrolizumab for people with metastatic melanoma. The aim is to see if this combination helps improve survival compared to a placebo.
We are studying whether ficerafusp alfa combined with pembrolizumab can effectively treat patients with recurrent or metastatic head and neck cancer. This trial aims to find the best dose and compare its effects to a placebo.
We are comparing a new treatment using your own bone marrow cells with standard care for diabetic patients with severe circulation problems. The goal is to see if this therapy improves tissue oxygen levels and overall health.
We are studying whether SRSD107 can effectively prevent blood clots in adults undergoing knee replacement surgery. We will also assess how safe it is compared to the standard treatment, enoxaparin.
We are studying a new treatment for patients with advanced NSCLC who have a specific mutation and did not respond to prior therapy. The goal is to see if this treatment can help shrink tumors and improve survival.
We are investigating the safety and early effectiveness of the DNA-repair inhibitor GSK4418959 in adults with specific solid tumors. This study looks at the drug alone and with other cancer treatments to see how well it works.
We are evaluating the effects of tibulizumab on skin lesions and quality of life for adults with hidradenitis suppurativa. The study also looks at the safety and tolerability of this treatment.
We are investigating a new medication, tebapivat, to see if it helps improve anemia in people with sickle cell disease. The study will also look at its safety and effects on fatigue and pain.
We are studying if adding liver-directed radiotherapy to the standard treatment helps patients with metastatic uveal melanoma live longer and stay on treatment longer. This trial also looks at how the body responds to the combination therapy.
We are examining the long-term safety and effectiveness of APG777 in patients with moderate-to-severe atopic dermatitis who have already used this treatment. The goal is to see how well it works over time and if it remains safe.
We are evaluating a new medication for patients with advanced non-small cell lung cancer who have a specific genetic deletion. The study aims to understand how well it works and its safety compared to previous treatments.
We are investigating the safety and tolerability of ALKS 2680 for people with narcolepsy and idiopathic hypersomnia. The study also looks at its effects on excessive daytime sleepiness and cataplexy.
We are studying a new nebulized treatment for adults with cystic fibrosis and chronic Pseudomonas lung infection. The goal is to see if it helps reduce the infection and improve lung function and quality of life.