Search Clinical Trials in the European Union

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1401-1420 of 2,251 trials

Mindfulness Training and Oxytocin for Stress Relief

We are studying whether combining oxytocin treatment with mindfulness training can better reduce stress in adults with high stress levels. This trial will measure changes in psychological distress and other related factors.

Psychological Distress≤3 monthsEfficacy phase (II)≤5 visitsNo PlaceboStandard MedicinesCost Reimbursement

Cataract Surgery: Clobetasol vs. Prednisolone in Young Children

We are studying a new eye treatment for inflammation after cataract surgery in children aged 0 to 3 years. The goal is to see if it is safer and more effective than the standard treatment.

Eye Inflammation and Pain>2 yearsConfirmation phase (III)≤5 visitsNo PlaceboStandard MedicinesOphthalmologyPediatrics

Neurodegenerative Disorders: Tau PET Imaging Study

We are exploring a new imaging method to identify early signs of neurodegenerative diseases in at-risk individuals. The study aims to understand how tau protein relates to cognitive changes and different types of dementia.

Neurodegenerative Diseases>2 yearsEfficacy phase (II)No PlaceboInvestigational MedicinesNeurology

Advanced Sarcoma: NKG2D CAR-T Cell Therapy

We are testing a new type of immune cell therapy for children and young adults with advanced sarcoma. The study aims to see if this treatment is safe and effective in reducing tumor size.

Sarcoma>2 yearsSafety phase (I)No PlaceboInvestigational MedicinesOncology

Peritonitis Treatment: Pentaglobin® Study

We are investigating whether Pentaglobin® can improve organ function and reduce the risk of death in patients recovering from peritonitis. This study looks at changes in health over time after infection control.

SepsisSeptic ShockSeptic Peritonitis3-6 monthsEfficacy phase (II)No PlaceboStandard MedicinesInfectious DiseasesInternal Medicine

Gastric Bypass Surgery: Tranexamic Acid Study

We are investigating whether giving Tranexamic acid during gastric bypass surgery helps reduce bleeding in patients with morbid obesity. This could lead to safer surgical procedures.

Morbid Obesity1-2 yearsConfirmation phase (III)No PlaceboStandard MedicinesInternal MedicineOrthopedics and Traumatology

BRAF Alterations in Cancer: FORE8394 Treatment Study

We are testing the drug FORE8394 in patients with advanced solid tumors or specific brain tumors that have BRAF alterations. The goal is to see if it can effectively treat these cancers.

BRAF Gene MutationEfficacy phase (II)16-20 visitsNo PlaceboInvestigational MedicinesPartially RemoteOncology

Hernia Repair: Comparing Pain Relief Techniques

We are studying whether giving a specific pain relief injection before or after hernia surgery helps reduce chronic pain and the need for pain medications. This trial is for patients undergoing open inguinal hernia mesh repair.

Chronic Pain After Hernia Surgery1-2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesInternal MedicineOrthopedics and Traumatology

YTB323 for Treatment-Resistant Generalized Myasthenia Gravis

We are studying the safety and effects of YTB323 in patients with treatment-resistant generalized myasthenia gravis. This research aims to understand how the drug works in the body and its potential to improve symptoms.

Myasthenia Gravis1-2 yearsSafety phase (I)Efficacy phase (II)6-10 visitsPost-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementInternal MedicineNeurology

Pleural Empyema: Surgery vs. Drainage

We are studying whether surgery is more effective than drainage for treating pleural empyema. This trial will help us understand the best approach for patients with this condition.

Pleural Empyema>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesInternal MedicinePulmonology

Migraine Prevention: Comparing Common Medications

We are studying how well different medications prevent migraines in primary care patients. This trial aims to find out which treatment reduces migraine days and improves quality of life.

Migraine Headaches≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesInternal MedicineNeurology

Cytoreductive Surgery: HiPRESS Study

We are testing if low-dose argipressin can reduce fluid use and improve recovery during surgery for cancer treatment. This study compares it to standard treatment to see which is better for patients.

Disseminated Cancer≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesGastroenterologyInternal MedicineOrthopedics and Traumatology

Frozen Embryo Transfer: The Role of Corpus Luteum

We are studying how the presence of the corpus luteum affects pregnancies from frozen embryo transfers. This research may help us understand its impact on maternal and fetal health.

Infertility6-12 monthsMonitoring phase (IV)11-15 visitsNo PlaceboStandard MedicinesGynecology and Obstetrics

Ataxia Telangiectasia: EryDex Safety Study

We are assessing the safety and tolerability of EryDex in individuals with Ataxia Telangiectasia. Additionally, we’re exploring its potential effects on neurological symptoms.

Ataxia Telangiectasia (A-T)1-2 yearsConfirmation phase (III)Post-Trial Drug AccessNo PlaceboStandard MedicinesPartially RemoteInternal MedicineNeurology

Advanced Solid Tumors: MCLA-158 (Petosemtamab) Study

We are testing a new treatment called MCLA-158 for people with advanced solid tumors to see how well it works and how safe it is. This study looks at its effects alone and in combination with other therapies.

Metastatic Colorectal CancerMalignant Solid TumorSafety phase (I)Efficacy phase (II)Post-Trial Drug AccessNo PlaceboStandard MedicinesOncology

Skin Cancer Treatment: Nivolumab and Relatlimab Study

We are studying the effects of Nivolumab alone and in combination with Relatlimab for patients with advanced squamous cell carcinoma of the skin. This trial aims to find out which treatment may help control the disease better.

Locally Advanced/Metastatic Squamous Cell Carcinoma of the Skin>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesDermatologyOncology

Retinitis Pigmentosa: Stem Cell Eye Treatment

We are testing a new stem cell-based treatment for people with retinitis pigmentosa to see if it is safe and tolerable. The study also aims to evaluate its potential to improve vision.

Retinitis Pigmentosa1-2 yearsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesOphthalmology

Stroke Prevention: Low Dose Colchicine Study

We are investigating whether low dose colchicine can help prevent future strokes and other major vascular events in patients with a history of stroke due to atherosclerosis.

Cardiovascular Diseases>2 yearsConfirmation phase (III)6-10 visitsNo PlaceboStandard MedicinesCardiologyInternal Medicine

Lung Cancer Treatment: Nivolumab + Relatlimab with Chemotherapy

We are studying if a new combination treatment helps people with advanced non-small cell lung cancer live longer compared to standard treatment. This trial is for those whose cancer has spread or returned after previous treatment.

Advanced Non-Small Cell Lung Cancer>2 yearsConfirmation phase (III)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementOncology

Osteoarthritis Behind the Kneecap: Nasal Cartilage Implantation

We are studying a new nasal cartilage treatment for people with osteoarthritis behind the kneecap to see if it improves recovery compared to standard care. The trial will also assess safety and how well the treatment works over time.

Knee OsteoarthritisPatellofemoral Osteoarthritis>2 yearsEfficacy phase (II)6-10 visitsNo PlaceboInvestigational MedicinesInternal MedicineOrthopedics and Traumatology