Search Clinical Trials in the European Union

Duration
Visits
Phase
Intake methods
Standard Medicines
Drugs
Locations
Clinical Specialty
1101-1120 of 1,782 trials

Skin Cancer Treatment: Nivolumab and Relatlimab Study

We are studying the effects of Nivolumab alone and in combination with Relatlimab for patients with advanced squamous cell carcinoma of the skin. This trial aims to find out which treatment may help control the disease better.

Locally Advanced/Metastatic Squamous Cell Carcinoma of the Skin>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesDermatologyOncology

Stroke Prevention: Low Dose Colchicine Study

We are investigating whether low dose colchicine can help prevent future strokes and other major vascular events in patients with a history of stroke due to atherosclerosis.

Cardiovascular Diseases>2 yearsConfirmation phase (III)6-10 visitsNo PlaceboStandard MedicinesCardiologyInternal Medicine

Palmo-Plantars Warts: HPV Vaccine Study

We are testing a nonavalent HPV vaccine to see if it helps people with difficult-to-treat warts on their hands and feet. The study aims to improve wart clearance, pain, and overall quality of life.

HPV Vaccine>2 yearsConfirmation phase (III)≤5 visitsStandard MedicinesPartially RemoteDermatologyInfectious Diseases

Idiopathic Inflammatory Myopathies: Upadacitinib Study

We are testing whether Upadacitinib can help patients with idiopathic inflammatory myopathies maintain stable disease after stopping IVIG treatment. The study compares its effects to a placebo over 16 weeks.

PolymyositisDermatomyositisAntisynthetase Syndrome3-6 monthsEfficacy phase (II)6-10 visitsStandard MedicinesDermatologyRheumatology

Postoperative Pain Relief: PENG Block for Hip Surgery

We are studying whether a nerve block can reduce pain after hip surgery called peri-acetabular osteotomy. This trial compares the nerve block to a placebo to see if it helps patients feel better and use fewer pain medications.

Periacetabular Osteotomy1-2 yearsMonitoring phase (IV)Standard MedicinesOrthopedics and TraumatologyOtolaryngology

Heart Attack Recovery: Bempedoic Acid Study

We are investigating whether adding bempedoic acid to standard cholesterol medications helps heart attack patients reach their cholesterol goals. This study aims to improve treatment for those not meeting guidelines with current therapies.

Heart Attack1-2 yearsConfirmation phase (III)≤5 visitsNo PlaceboStandard MedicinesCardiologyInternal Medicine

Immunotherapy for Advanced Cancer: Standard vs. Reduced Dose

We are comparing standard immunotherapy treatment with a less frequent dosing schedule for patients with advanced cancer. The goal is to see if the reduced dose is just as effective and to evaluate its impact on quality of life and safety.

Advanced or Metastatic Cancer>2 yearsConfirmation phase (III)11-15 visitsNo PlaceboStandard MedicinesOncology

Atrial Fibrillation: Dapagliflozin Treatment Study

We are investigating if dapagliflozin can help prevent the return of atrial fibrillation after cardioversion compared to usual care. This study aims to see how well it works in prolonging the time before atrial fibrillation recurs.

Atrial Fibrillation≤3 monthsConfirmation phase (III)Monitoring phase (IV)No PlaceboStandard MedicinesCardiologyInternal Medicine

Metastatic Colorectal Cancer: Trifluridine/Tipiracil with Panitumumab vs. Bevacizumab

We are studying two treatment combinations to find out which one works better for people with metastatic colorectal cancer. The trial also looks at safety and how treatments affect patients' quality of life.

Metastatic Colorectal Cancer>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesPartially RemoteOncology

Angiosarcoma and Undifferentiated Pleomorphic Sarcoma: Propranolol and Pembrolizumab Study

We are studying the effects of a new treatment combining propranolol and pembrolizumab for patients with advanced Angiosarcoma and Undifferentiated Pleomorphic Sarcoma. The goal is to see if this combination improves survival and quality of life.

Advanced Angiosarcoma and Undifferentiated Pleomorphic Sarcoma3-6 monthsEfficacy phase (II)No PlaceboStandard MedicinesOncology

Breast Cancer Prevention: Denosumab for Women with BRCA1 Mutation

We are studying whether Denosumab can help prevent breast cancer in women carrying a BRCA1 mutation. This trial compares its effects to a placebo to see if it reduces cancer risk.

Breast Cancer Prevention in BRCA1 Mutation Carriers>2 yearsConfirmation phase (III)11-15 visitsStandard MedicinesPartially RemoteHematologyOncology

Acute Myocarditis: Ibuprofen vs. Standard Pain Relief

We are studying whether ibuprofen can better improve heart health compared to regular pain relief in patients with acute myocarditis. This trial focuses on how these treatments affect heart imaging results after six months.

Acute Myocarditis>2 yearsMonitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesCardiologyInternal Medicine

Leiomyosarcoma: Trabectedin vs. Gemcitabine

We are comparing two treatments, Trabectedin and Gemcitabine, for patients with advanced leiomyosarcoma who have already received chemotherapy. The goal is to see which treatment works better in slowing down cancer growth and improving survival.

Leiomyosarcoma>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesOncology

Giant Cell Arteritis and Polymyalgia Rheumatica: Hydrocortisone Study

We are investigating whether hydrocortisone can help patients with GCA and PMR who report symptoms of adrenal insufficiency after stopping glucocorticoids. This study aims to provide better treatment options for these patients.

Tertiary Adrenal Insufficiency>2 yearsMonitoring phase (IV)≤5 visitsStandard MedicinesCost ReimbursementPartially RemoteEndocrinologyRheumatology

Cerebrolysin for CADASIL Patients

We are studying whether Cerebrolysin is safe and effective for individuals with genetically confirmed CADASIL. This trial compares it to a placebo to understand its overall benefits.

CADASIL>2 yearsEfficacy phase (II)>20 visitsStandard MedicinesNeurology

Efgartigimod for Children with Generalized Myasthenia Gravis

We are studying a new treatment for children aged 2 to under 18 with generalized myasthenia gravis. The trial will evaluate the safety, dosing, and effects of this treatment on their daily lives.

Myasthenia Gravis6-12 monthsEfficacy phase (II)Confirmation phase (III)6-10 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesCost ReimbursementInternal MedicineNeurology

Chronic Rhinosinusitis with Nasal Polyps: Tezepelumab Study

We are investigating how tezepelumab affects symptoms in adults with chronic rhinosinusitis and nasal polyps. The study looks at changes in nasal congestion, sense of smell, and overall quality of life.

Chronic Rhinosinusitis with Nasal Polyps3-6 monthsConfirmation phase (III)6-10 visitsNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteOtolaryngologyPulmonology

Preventing Constipation After Hip Surgery: Laxative Study

We are exploring which laxatives work best to prevent constipation in patients recovering from hip fracture surgery. This research aims to improve comfort and recovery after surgery.

Hip Fracture>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesGastroenterologyOrthopedics and Traumatology

Glucose Distribution in Severely Burned Adults

We are studying how glucose is distributed in the bodies of severely burned adults during their first few days of treatment. This research may help us understand its relationship with other health factors and improve patient care.

Severe Burns>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesEndocrinologyInternal MedicineOrthopedics and Traumatology

Rectal Cancer: Valproic Acid with Radiotherapy and Capecitabine

We are studying whether adding valproic acid to standard radiotherapy and capecitabine improves tumor response in patients with low to moderate risk rectal cancer before surgery. This trial also examines the impact on survival and quality of life.

Rectal CancerSafety phase (I)Efficacy phase (II)No PlaceboStandard MedicinesOncology