Search Clinical Trials in the European Union

Duration
≤5 visits
Phase
Intake methods
Benefits
Drugs
Locations
Clinical Specialty
181-200 of 525 trials

Cancer Treatment: PET Tracers and T Cell Activity

We are studying how two PET tracers relate to T cell changes in cancer patients before surgery. This research may help us understand T cell activation and its impact on tumor response.

Breast CancerEsophageal CancerMelanoma3-6 monthsEfficacy phase (II)Confirmation phase (III)≤5 visitsNo PlaceboInvestigational MedicinesCost ReimbursementHematologyOncology

Melanoma: [68Ga]Ga-FAPI PET/CT Imaging Study

We are testing a new imaging method to see how well immune checkpoint inhibitor therapy works in patients with advanced melanoma. This study aims to improve response evaluation during treatment.

Malignant Melanoma6-12 monthsEfficacy phase (II)≤5 visitsNo PlaceboInvestigational MedicinesDermatologyOncology

Tick-Borne Encephalitis: Novel Cytokine Release Assay

We are studying a new test to measure immune responses to Tick-Borne Encephalitis in healthy and immunosuppressed individuals. This research aims to improve understanding of how well the immune system responds to the virus and vaccination.

Tick-borne Encephalitis>2 yearsMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesAllergologyInfectious Diseases

MEPENDAX: Axitinib and Etoposide for Pediatric Brain Tumors

We are studying a new treatment combining axitinib and oral etoposide for children and young adults with relapsing medulloblastoma or ependymoma. The goal is to find the safest dose and see if it helps improve survival.

MedulloblastomaEpendymoma>2 yearsSafety phase (I)Efficacy phase (II)≤5 visitsNo PlaceboInvestigational MedicinesNeurologyOncologyPediatrics

Bipolar Disorder Type II: Lithium vs. Lamotrigine Study

We are comparing the effects of lithium and lamotrigine on mood stabilization in people with bipolar disorder type II. The goal is to see which treatment may better reduce symptoms and improve daily functioning.

Bipolar Disorder, Type II1-2 yearsMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesPartially RemotePsychiatry

Atrial Fibrillation: New Drug Treatment After Stent Surgery

We are studying whether a simpler medication regimen can safely prevent blood clots and serious heart issues in patients with irregular heartbeat after coronary stent implantation. This trial compares it to the current standard treatment involving multiple medications.

Acute Coronary SyndromeAtrial FibrillationAtrial Flutter>2 yearsConfirmation phase (III)≤5 visitsNo PlaceboStandard MedicinesPartially RemoteCardiologyInternal Medicine

Rheumatoid Arthritis: JAK Inhibitor Dose Tapering Study

We are exploring whether reducing the dose of JAK inhibitors helps maintain low disease activity in rheumatoid arthritis patients. This study will also look at the impact on pain, function, and overall quality of life.

Rheumatoid Arthritis>2 yearsMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesRheumatology

Ibrutinib for Autoimmune Hemolytic Anemia in CLL Patients

We are studying whether ibrutinib can effectively treat autoimmune hemolytic anemia in patients with chronic lymphocytic leukemia or similar conditions. The trial will also look at the safety and quality of life during treatment.

Chronic Lymphocytic Leukemia (CLL)>2 yearsEfficacy phase (II)≤5 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesHematologyOncology

Diabetic Macular Edema: Faricimab Treatment Study

We are exploring whether Faricimab can improve vision in patients with diabetic macular edema. The study also examines changes in eye health and treatment frequency over 12 months.

Diabetic Macular Edema>2 yearsMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesEndocrinologyOphthalmology

Oocyte Cryopreservation: Random Start Ovarian Stimulation

We are comparing a new method of ovarian stimulation with a traditional approach for women planning to freeze their eggs. This study aims to determine if the new method is equally effective.

Prevention of Female Infertility≤3 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesEndocrinologyGynecology and Obstetrics

Chemotherapy Dose Adjustment for DPD-Deficient Gastrointestinal Cancer Patients

We are studying how to safely adjust chemotherapy doses for patients with gastrointestinal cancers who lack a specific liver enzyme. This may help reduce severe side effects during treatment.

Gastrointestinal Cancer Patients Starting Chemotherapy>2 yearsEfficacy phase (II)≤5 visitsNo PlaceboStandard MedicinesGastroenterologyOncology

Tranexamic Acid for Reducing Blood Transfusions in Abdominal Surgery

We are studying whether Tranexamic Acid can lower blood loss and the need for blood transfusions during major abdominal surgeries. This trial also examines safety and recovery outcomes for patients.

Intraoperative Bleeding1-2 yearsMonitoring phase (IV)≤5 visitsStandard MedicinesHematologyOrthopedics and Traumatology

Inebilizumab for Children with Neuromyelitis Optica Spectrum Disorder

We are studying how the medication inebilizumab affects children and adolescents with NMOSD. The trial will help us learn about its safety and how it impacts their health and daily life.

Neuromyelitis Optica Spectrum Disorder1-2 yearsEfficacy phase (II)≤5 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesNeurology

Meniscal Pain Relief: Betamethasone Infiltration Study

We are testing whether ultrasound-guided betamethasone injections can reduce pain in adults with degenerative meniscal injuries. This study compares the treatment to a placebo to assess its effectiveness and safety.

Meniscal Pain3-6 monthsConfirmation phase (III)≤5 visitsStandard MedicinesPartially RemoteInternal MedicineOrthopedics and Traumatology

Corneal Endothelial Transplantation: NSAIDs vs. Steroids

We are comparing two medication regimens to see if adding NSAIDs helps reduce inflammation and cystoid macular edema after corneal endothelial transplantation. This study is for patients undergoing this specific eye surgery.

Fuchs Dystrophy>2 yearsMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesOphthalmology

Thyroid Eye Disease: Sirolimus vs. Corticosteroids

We are comparing a new treatment called Sirolimus with corticosteroids for people with active thyroid eye disease. The goal is to see if Sirolimus is more effective and has fewer side effects.

Thyroid Eye Disease≤3 monthsConfirmation phase (III)≤5 visitsNo PlaceboStandard MedicinesPartially RemoteEndocrinologyOphthalmology

Rheumatoid Arthritis: Proactive Drug Monitoring Study

We are investigating whether proactive monitoring of a TNF inhibitor helps adults with rheumatoid arthritis maintain better disease control without flare-ups compared to standard care.

Rheumatoid Arthritis1-2 yearsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesRheumatology

Advanced Lung Cancer: STX-241 Study

We are testing a new oral anticancer drug, STX-241, for patients with advanced non-small cell lung cancer resistant to standard treatments. The goal is to evaluate its safety and potential effectiveness.

Metastatic Non-Small Cell Lung CancerSafety phase (I)Efficacy phase (II)≤5 visitsPost-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementOncologyPulmonology

Behçet's Syndrome: Steroids Plus Anticoagulants Study

We are investigating whether adding anticoagulants to steroid therapy helps reduce the risk of deep venous thrombosis relapse in people with Behçet's syndrome. This study will also look at safety and quality of life.

Behcet's Syndrome>2 yearsEfficacy phase (II)≤5 visitsStandard MedicinesHematologyInternal MedicineRheumatology

Niemann-Pick Disease Type C: N-Acetyl-L-Leucine Study

We are investigating whether N-Acetyl-L-Leucine can improve symptoms and quality of life for individuals with Niemann-Pick disease type C. The study also looks at the safety of this treatment for both older and younger patients.

Niemann-Pick Disease Type C3-6 monthsConfirmation phase (III)≤5 visitsPost-Trial Drug AccessInvestigational MedicinesPartially RemoteHematologyNeurology