Search Clinical Trials in the European Union

Duration
6-10 visits
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281-300 of 604 trials

Myelofibrosis: Selinexor Treatment Study

We are studying the effects of selinexor in patients with myelofibrosis who haven't been treated with JAK inhibitors. The goal is to see if it helps improve symptoms and overall health.

MyelofibrosisModerate ThrombocytopeniaEfficacy phase (II)6-10 visitsNo PlaceboInvestigational MedicinesCost ReimbursementHematology

Advanced Non-Small Cell Lung Cancer: BAY 2927088 Study

We are investigating how well BAY 2927088 works and its safety compared to standard treatment for patients with advanced non-small cell lung cancer with HER2 mutations.

Advanced Non-Small Cell Lung Cancer with HER2 MutationConfirmation phase (III)6-10 visitsPost-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteOncology

Oral Propranolol for Preventing Eye Issues in Premature Infants

We are studying whether oral propranolol can help extremely preterm infants lower their risk of developing threshold retinopathy of prematurity. This research aims to improve safety and reduce the need for additional treatments.

Retinopathy of Prematurity>2 yearsEfficacy phase (II)6-10 visitsStandard MedicinesPartially RemoteOphthalmologyPediatrics

Crohn's Disease: EXL01 for Post-Surgery Recurrence Prevention

We are studying whether EXL01 can help prevent the return of Crohn's disease in patients after surgery. This trial compares its effects to a placebo to assess safety and effectiveness.

Crohn's Disease3-6 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesPartially RemoteGastroenterologyInternal Medicine

Colchicine for Knee and Hip Osteoarthritis

We are studying whether colchicine can help reduce the need for knee or hip replacements in people with osteoarthritis. The trial also looks at its effects on pain, physical function, and overall quality of life.

Osteoarthritis>2 yearsConfirmation phase (III)6-10 visitsStandard MedicinesCost ReimbursementPartially RemoteOrthopedics and TraumatologyRheumatology

Dental Implant Surgery: Antibiotics Study

We are investigating whether taking antibiotics helps patients recover better after dental implant surgery with bone regeneration and sinus elevation. This study compares the effects of antibiotics to a placebo on patient outcomes.

Implant Surgery with Guided Bone Regeneration6-12 monthsMonitoring phase (IV)6-10 visitsInvestigational MedicinesGynecology and ObstetricsInfectious DiseasesOrthopedics and TraumatologyOtolaryngology

Glycopyrronium for Asthma in Children

We are studying how well glycopyrronium works for children aged 6 to under 12 with asthma. The trial will also look at its safety and any side effects.

Asthma3-6 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesCost ReimbursementPediatricsPulmonology

Ulcerative Colitis: Filgotinib for Kids and Teens

We are studying the effects of filgotinib in children and teenagers with moderately to severely active ulcerative colitis. The trial aims to see if it helps achieve remission and improves quality of life.

Ulcerative Colitis1-2 yearsConfirmation phase (III)6-10 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteGastroenterologyPediatrics

RECLAIM: Treatments for Long COVID

We are studying different treatments for people suffering from long COVID to see how they improve physical and mental health. The trial will also assess specific symptoms like fatigue and cognitive difficulties.

Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)3-6 monthsConfirmation phase (III)6-10 visitsStandard MedicinesPartially RemoteInfectious DiseasesInternal Medicine

Sodium Thiosulfate Injections for Ectopic Calcifications

We are studying whether injections of sodium thiosulfate can help reduce calcifications and ossifications in patients with certain autoimmune conditions. This trial will also look at the treatment's safety and its impact on pain and quality of life.

Ectopic Calcification and Ossification>2 yearsEfficacy phase (II)6-10 visitsNo PlaceboInvestigational MedicinesCost ReimbursementDermatologyRheumatology

NVDX3 Implant: Long-Term Safety Study

We are examining the long-term safety of the NVDX3 osteogenic implant made from human tissue. This study aims to ensure it is safe for patients who may need this type of treatment.

Low Grade Degenerative Lumbar SpondylolisthesisDistal Radius Fracture>2 yearsSafety phase (I)Efficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesOrthopedics and Traumatology

Cirrhosis: Carvedilol for Prevention

We are studying whether low-dose carvedilol can help prevent complications or death in patients with asymptomatic cirrhosis. This trial focuses on individuals with specific liver conditions to see if the medication is effective and safe.

Alcoholic Cirrhosis>2 yearsMonitoring phase (IV)6-10 visitsStandard MedicinesCost ReimbursementHepatologyInternal Medicine

Bronchiectasis: 7% Hypertonic Saline Inhalation

We are studying whether inhaling a 7% hypertonic saline solution before physiotherapy helps patients with bronchiectasis clear mucus more effectively. We’ll also look at its impact on cough, quality of life, and any side effects.

Bronchiectasis1-2 yearsMonitoring phase (IV)6-10 visitsNo PlaceboInvestigational MedicinesInternal MedicinePulmonology

Multiple Sclerosis in Kids: Ofatumumab and Siponimod Study

We are comparing two new treatments, ofatumumab and siponimod, to fingolimod in children with multiple sclerosis. The study aims to see if these new options are as effective and safe for managing their condition.

Multiple Sclerosis>2 yearsConfirmation phase (III)6-10 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementNeurologyPediatrics

Dexamethasone for Congenital Adrenal Hyperplasia in Pregnancy

We are studying whether a lower dose of dexamethasone can effectively prevent prenatal complications in female babies with congenital adrenal hyperplasia. We will also monitor the health of mothers and their children during and after pregnancy.

Congenital Adrenal HyperplasiaEfficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesPartially RemoteEndocrinologyGynecology and Obstetrics

Lung Fibrosis: ENV-101 Treatment Study

We are testing a new medication, ENV-101, for people with lung fibrosis to see if it improves lung function and overall health. The study will also look at the safety of this treatment.

Idiopathic Pulmonary Fibrosis6-12 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesCost ReimbursementPartially RemotePulmonology

Fecal Microbiota Transplantation for Crohn’s Disease After Anti-TNF Withdrawal

We are studying whether fecal microbiota transplantation can help maintain remission in Crohn’s disease patients after stopping anti-TNF treatment. This trial compares FMT to a sham procedure to assess its effectiveness in preventing relapse and improving gut health.

Crohn's DiseaseConfirmation phase (III)Monitoring phase (IV)6-10 visitsInvestigational MedicinesGastroenterologyInternal Medicine

Severe Infections in ICU: Comparing Antibiotics

We are studying whether piperacillin-tazobactam or temocillin can effectively treat severe infections caused by certain bacteria in ICU patients, compared to standard carbapenem treatment. This research may help improve treatment options for critically ill patients.

ESBL-Producing Bacteria Infection>2 yearsConfirmation phase (III)6-10 visitsNo PlaceboInvestigational MedicinesPartially RemoteInfectious DiseasesInternal Medicine

Type 1 Diabetes: Metformin's Impact on Arterial Health

We are studying whether metformin can slow down artery calcification and improve blood flow in people with type 1 diabetes who do not have chronic kidney disease. This research may help us understand how to better manage cardiovascular risks in these patients.

Vascular CalcificationType 1 Diabetes>2 yearsConfirmation phase (III)6-10 visitsInvestigational MedicinesCardiologyEndocrinologyInternal Medicine

Antisynthetase Syndrome: Cyclophosphamide vs Tacrolimus

We are comparing the effects of Cyclophosphamide and Azathioprine against Tacrolimus in patients with antisynthetase syndrome-related lung disease. The goal is to see which treatment better improves lung function and quality of life.

Interstitial Lung DiseaseConfirmation phase (III)6-10 visitsNo PlaceboStandard MedicinesPulmonologyRheumatology