Search Clinical Trials in the European Union

6-12 months
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221-240 of 397 trials

Kidney Transplant Rejection: Everolimus Study

We are studying whether everolimus can help kidney transplant patients with a specific type of rejection maintain kidney function and reduce damage. This trial looks at its effects over six months.

Kidney Failure6-12 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesNephrology

Efgartigimod for Children with Generalized Myasthenia Gravis

We are studying a new treatment for children aged 2 to under 18 with generalized myasthenia gravis. The trial will evaluate the safety, dosing, and effects of this treatment on their daily lives.

Myasthenia Gravis6-12 monthsEfficacy phase (II)Confirmation phase (III)6-10 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesCost ReimbursementInternal MedicineNeurology

Hypertrophic Cardiomyopathy: Sotagliflozin Study

We are investigating whether sotagliflozin can improve symptoms in people with hypertrophic cardiomyopathy. The study also looks at the safety of this treatment compared to a placebo.

Hypertrophic Cardiomyopathy6-12 monthsConfirmation phase (III)6-10 visitsInvestigational MedicinesCost ReimbursementCardiologyInternal Medicine

Semaglutide for Obesity and Resistant Hypertension

We are exploring whether semaglutide can help people with obesity and resistant hypertension better control their blood pressure compared to a placebo. This study aims to assess if this approach is feasible.

Resistant HypertensionObesity6-12 monthsConfirmation phase (III)Standard MedicinesCost ReimbursementPartially RemoteCardiologyEndocrinologyInternal Medicine

Pulmonary Hypertension: Mosliciguat Study

We are testing the medication Mosliciguat for individuals with pulmonary hypertension related to interstitial lung disease. The study aims to see if it helps improve heart function and walking ability.

Pulmonary Hypertension6-12 monthsEfficacy phase (II)>20 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteCardiologyPulmonology

Venous Thromboembolism in Cancer: Abelacimab vs. Dalteparin

We are studying whether a new medication, abelacimab, can effectively prevent blood clots in patients with gastrointestinal or genitourinary cancer. This trial compares it to the standard treatment, dalteparin.

Venous Thromboembolism (VTE)6-12 monthsEfficacy phase (II)Confirmation phase (III)6-10 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteHematologyOncology

Craniotomy Pain Management: S-Ketamine Study

We are investigating whether adding s-ketamine to standard pain relief helps reduce opioid use and improve pain control after craniotomy in patients with drug-resistant epilepsy.

Post-Craniotomy Headache6-12 monthsMonitoring phase (IV)Standard MedicinesNeurologyOtolaryngologyPsychiatry

Sacituzumab Govitecan with Bevacizumab for Brain Metastases in Lung Cancer

We are studying a combination of two medications for patients with brain metastases from non-small cell lung cancer. The goal is to see how well this treatment works in reducing tumor size and improving patient outcomes.

Lung Cancer6-12 monthsEfficacy phase (II)11-15 visitsPost-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementNeurologyOncology

PD-1 Antibody for Metastatic Solid Tumors

We are testing a new method of delivering a PD-1 antibody directly into the spinal fluid for patients with metastatic solid tumors and leptomeningeal disease. The study aims to determine the safe dosage and its potential impact on survival.

Leptomeningeal Disease6-12 monthsSafety phase (I)Efficacy phase (II)6-10 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesNeurologyOncology

Extra-Mammary Paget's Disease: PAGETEX Device Study

We are studying the PAGETEX device to see if it helps control Extra-Mammary Paget's Disease of the vulva. The trial will also look at pain levels, quality of life, and patient satisfaction during treatment.

Paget's Disease of the Vulva6-12 monthsEfficacy phase (II)No PlaceboStandard MedicinesGynecology and ObstetricsOncology

Caffeine Treatment for Early Alzheimer's Disease

We are studying whether a 30-week caffeine treatment can help improve thinking and memory in people with early to moderate Alzheimer's disease. This trial compares the effects of caffeine to a placebo to see if it makes a difference.

Alzheimer's Disease6-12 monthsConfirmation phase (III)Investigational MedicinesPartially RemoteNeurology

Metycor Study for Autonomous Cortisol Secretion

We are testing a new treatment to see if it improves blood pressure, glucose levels, and overall health in patients with autonomous cortisol secretion. The study also looks at effects on weight, bone health, and quality of life.

Mild Autonomous Cortisol Secretion6-12 monthsMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesPartially RemoteCardiologyEndocrinologyInternal Medicine

Borderline Personality Disorder and ADHD: BI 3031185 Study

We are testing how well BI 3031185 is tolerated by individuals with borderline personality disorder or ADHD. This study aims to gather information on its safety and side effects.

Borderline Personality DisorderAttention Deficit Hyperactivity Disorder6-12 monthsSafety phase (I)Psychiatry

Chronic Immune Thrombocytopenia: Mezagitamab Injection

We are studying a new injection, mezagitamab, for adults with chronic immune thrombocytopenia to see if it can improve platelet counts and reduce symptoms compared to a placebo.

Primary Immune Thrombocytopenia6-12 monthsConfirmation phase (III)16-20 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementHematology

Small Cell Lung Cancer: ZL-1310 Study

We are testing different doses of ZL-1310 in patients with small cell lung cancer. The goal is to find a suitable dose and see how well the body tolerates and processes the medication.

Small Cell Lung Cancer6-12 monthsSafety phase (I)Oncology

Giant Cell Arteritis: Imaging Study with [18F]fluor-PEG-folate

We are investigating how well a special imaging technique shows changes in arteries of patients with giant cell arteritis before and after treatment. This may help us understand the disease better and improve future care.

Giant Cell Arteritis6-12 monthsEfficacy phase (II)≤5 visitsNo PlaceboInvestigational MedicinesCost ReimbursementRheumatology

Erectile Dysfunction: Botulinum Toxin Injection Study

We are testing a new injection treatment for men with erectile dysfunction that hasn't improved with standard medications. The study will help us understand its effectiveness and any side effects.

Erectile Dysfunction6-12 monthsEfficacy phase (II)Standard MedicinesUrology

Dexmedetomidine for Pain Management in Pediatric Surgery

We are studying whether adding intravenous dexmedetomidine to local anesthesia helps reduce pain after surgery in children. This trial will also look at how it affects recovery and any side effects.

Loco-regional Anesthesia in Pediatric Surgery6-12 monthsEfficacy phase (II)Standard MedicinesPartially RemoteInternal MedicineOtolaryngologyPediatrics

Pancreatic Cancer: Durvalumab and Rintatolimod Combination

We are studying a new treatment combining durvalumab and rintatolimod for patients with metastatic pancreatic ductal adenocarcinoma. The goal is to see if this combination is safe and improves survival and quality of life.

Metastatic Pancreatic Cancer6-12 monthsSafety phase (I)Efficacy phase (II)>20 visitsNo PlaceboInvestigational MedicinesGastroenterologyOncology

Reducing Anxiety in Children: Multimedia vs. Midazolam

We are studying whether using an iPad can help reduce anxiety in young children before surgery, compared to traditional medication. This trial focuses on children aged 1 to 8 years undergoing day-care procedures.

Perioperative Anxiety in Children6-12 monthsMonitoring phase (IV)Standard MedicinesCost ReimbursementInternal MedicineOtolaryngologyPediatricsPsychiatry