Search Clinical Trials in the European Union

6-12 months
Visits
Phase
Intake methods
Benefits
Drugs
Locations
Clinical Specialty
1-20 of 397 trials

Adrenocortical Carcinoma: Mitotane Treatment Study

We are comparing standard mitotane therapy to mitotane combined with chemotherapy for patients at high risk of cancer recurrence after surgery. This study aims to find out which treatment helps patients live longer and maintain a better quality of life.

Adrenocortical Carcinoma6-12 monthsConfirmation phase (III)No PlaceboStandard MedicinesOncology

SPRING Rollover: Follow-Up Study

This study is for participants from the previous SPRING trial to assess ongoing effects and safety of the treatment. We aim to gather more information on its long-term benefits.

Non-Small Cell Lung Cancer6-12 monthsSafety phase (I)Efficacy phase (II)Oncology

Rheumatoid Arthritis: Abatacept vs. TNF Inhibitors

We are comparing a new treatment strategy using abatacept to the standard TNF inhibitors for patients with rheumatoid arthritis. The goal is to see which approach helps more patients achieve remission.

Rheumatoid Arthritis6-12 monthsConfirmation phase (III)≤5 visitsNo PlaceboStandard MedicinesInternal MedicineRheumatology

Chronic Wet Cough in Children: The AMIC Study

We are investigating whether antibiotics can help children with chronic wet cough and how different treatment durations affect their recovery. The study also looks at the role of gut and airway bacteria in their health.

Chronic Wet Cough in Young Children6-12 monthsMonitoring phase (IV)Standard MedicinesInfectious DiseasesPulmonology

Xenon Treatment for Brain Injury After Aneurysmal Subarachnoid Hemorrhage

We are investigating whether xenon gas can help protect the brain and improve recovery in patients who have experienced a specific type of brain bleed. This study will also look at the safety and effects of xenon on neurological outcomes.

Aneurysmal Subarachnoid Hemorrhage6-12 monthsEfficacy phase (II)No PlaceboStandard MedicinesPartially RemoteInternal MedicineNeurology

Post-Cardiac Arrest Shock: High-Dose Vitamin C Study

We are investigating whether early intravenous high-dose vitamin C can help patients who have suffered a cardiac arrest and are in shock. The study aims to see if this treatment reduces the need for blood pressure support and improves survival and recovery.

Cardiac Arrest6-12 monthsEfficacy phase (II)No PlaceboStandard MedicinesCardiologyInternal Medicine

Diabetic Neuropathic Pain: Incobotulinumtoxin-A Injections

We are studying whether injections of incobotulinumtoxin-A can help relieve pain in people with diabetic neuropathic pain in their lower extremities. The trial will also look at how this treatment affects daily activities and overall quality of life.

Diabetic Peripheral Neuropathic Pain6-12 monthsEfficacy phase (II)Standard MedicinesDiabetologyEndocrinologyNeurology

ERASE PH-COPD: New Treatment for COPD

We are exploring a new approach for individuals with chronic obstructive pulmonary disease (COPD). The goal is to see if this treatment can improve breathing and overall health.

Pulmonary Hypertension6-12 monthsConfirmation phase (III)Pulmonology

Achilles Tendinopathy: NGI226 Microparticles Study

We are investigating the safety and effects of NGI226 microparticles for patients with Achilles tendinopathy. This study aims to see if it helps restore tendon strength compared to a placebo.

Achilles Tendinopathy6-12 monthsEfficacy phase (II)>20 visitsInvestigational MedicinesInternal MedicineOrthopedics and Traumatology

Children's Experience After General Anesthesia: Sedation Study

We are examining how different sedative medications impact children's recovery after surgery. The goal is to see if these medications can help reduce anxiety and improve overall comfort.

General Anesthesia and Sedation6-12 monthsConfirmation phase (III)6-10 visitsInvestigational MedicinesInternal MedicineOtolaryngologyPediatrics

Cognitive Deficits in Multiple Sclerosis: MODAFIMS Study

We are studying the effects of modafinil on cognitive deficits in people with Multiple Sclerosis. The trial aims to identify brain features that may predict treatment response and assess changes in cognitive function and quality of life.

Multiple Sclerosis6-12 monthsEfficacy phase (II)≤5 visitsNo PlaceboStandard MedicinesNeurology

NonAdvanced Systemic Mastocytosis: Bezuclastinib Study

We are testing a new oral medication, bezuclastinib, to see if it is effective and safe for patients with NonAdvanced Systemic Mastocytosis. This study compares the medication to a placebo to understand its potential benefits.

Systemic Mastocytosis6-12 monthsEfficacy phase (II)>20 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteAllergologyHematology

Dexamethasone for Moderate to Severe Depression

We are studying whether adding dexamethasone to standard depression treatment can improve symptoms for those with moderate to severe depression. This trial aims to assess its safety and effectiveness.

Depression6-12 monthsConfirmation phase (III)≤5 visitsInvestigational MedicinesCost ReimbursementPartially RemotePsychiatry

Chronic Lymphocytic Leukemia: Nemtabrutinib Study

We are comparing a new treatment called nemtabrutinib to standard options for patients with untreated chronic lymphocytic leukemia. The study aims to find out which treatment works better and is safer.

Small Lymphocytic Lymphoma (SLL) / Chronic Lymphocytic Leukemia (CLL)6-12 monthsConfirmation phase (III)>20 visitsNo PlaceboInvestigational MedicinesCost ReimbursementHematologyOncology

Asthma in Children: QMF149 vs. Budesonide

We are studying whether QMF149 can improve lung function and reduce asthma symptoms in children aged 6 to under 12 compared to Budesonide. This trial will help us understand which treatment works better for young patients.

Asthma6-12 monthsConfirmation phase (III)6-10 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPediatricsPulmonology

Acute Myeloid Leukemia: Hydroxyurea and Valproic Acid Study

We are investigating a new treatment combination for patients with acute myeloid leukemia or high-risk myelodysplastic syndrome who cannot receive standard chemotherapy. The study will assess safety, effectiveness, and quality of life.

Acute Myeloid Leukemia6-12 monthsSafety phase (I)Efficacy phase (II)No PlaceboStandard MedicinesHematologyOncology

Kidney Disease: ALE.F02 Treatment Study

We are testing a new intravenous treatment, ALE.F02, for patients with rapidly progressive glomerulonephritis linked to AAV. The study aims to see if it can help protect kidney function and assess its safety.

Rapidly Progressive Glomerulonephritis6-12 monthsEfficacy phase (II)Investigational MedicinesInternal MedicineNephrology

HPV Vaccine Effectiveness Study for Young Men

We are studying how well the bivalent HPV vaccine protects men aged 19-26 who have sex with men from anal HPV-16/18 infections. This research aims to understand vaccination impact and related factors.

HPV InfectionHealthy Participants6-12 monthsMonitoring phase (IV)No PlaceboStandard MedicinesInfectious Diseases

Focal-Onset Seizures: Study of XEN1101

We are testing a new medication, XEN1101, to see if it can help reduce the frequency of focal-onset seizures. This study compares its effects to a placebo in participants with this condition.

Focal Epilepsy6-12 monthsConfirmation phase (III)≤5 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteNeurology

Patient-Controlled Sedation for Perineal Laceration Repair

We are studying if adding propofol sedation improves comfort for women during the repair of grade I and II obstetric perineal lacerations. This trial aims to see if it reduces pain and discomfort compared to standard care.

Obstetric Perineal Lacerations6-12 monthsConfirmation phase (III)No PlaceboStandard MedicinesGynecology and ObstetricsOtolaryngology