Search Clinical Trials in the European Union

≤3 months
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21-40 of 240 trials

Fremanezumab for Pain in Complex Regional Pain Syndrome

We are studying whether fremanezumab can reduce pain in patients with Complex Regional Pain Syndrome compared to a placebo. The trial also examines how this treatment affects disease symptoms and function.

Complex Regional Pain Syndrome≤3 monthsEfficacy phase (II)≤5 visitsStandard MedicinesCost ReimbursementNeurology

PDA Treatment in Premature Infants: Acetaminophen and Ibuprofen Study

We are studying whether combining acetaminophen with ibuprofen helps extremely premature infants with a heart condition. The goal is to see if this combination reduces serious complications compared to ibuprofen alone.

Patent Ductus Arteriosus≤3 monthsEfficacy phase (II)No PlaceboInvestigational MedicinesCardiologyPediatrics

Metastatic Non-Small Cell Lung Cancer: Volrustomig Plus Chemotherapy

We are studying whether the new drug volrustomig combined with chemotherapy is more effective than pembrolizumab plus chemotherapy for patients with metastatic non-small cell lung cancer. This trial focuses on those with low PD-L1 levels.

Metastatic Non-Small Cell Lung Cancer≤3 monthsConfirmation phase (III)No PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteOncology

Delayed Gastric Emptying: Nicotine Patch Study

We are investigating whether a nicotine patch can help patients who have had pancreatoduodenectomy by reducing delayed gastric emptying. The study also looks at the safety and tolerability of this treatment compared to a placebo.

Pancreatoduodenectomy≤3 monthsEfficacy phase (II)Investigational MedicinesGastroenterologyInternal Medicine

Melatonin for Chronic Back Pain

We are studying whether melatonin can help reduce pain and improve sleep in people with chronic back pain. This trial compares melatonin to a placebo to see which is more effective.

Chronic Back Pain≤3 monthsConfirmation phase (III)≤5 visitsStandard MedicinesCost ReimbursementInternal MedicineOrthopedics and Traumatology

Fibrotic Interstitial Lung Disease: Morphine for Breathlessness

We are studying whether slow-release morphine can help reduce breathlessness and cough in patients with fibrotic interstitial lung disease. The goal is to see if it improves their overall quality of life.

Fibrotic Interstitial Lung Disease≤3 monthsMonitoring phase (IV)≤5 visitsStandard MedicinesCost ReimbursementPartially RemotePulmonology

Major Depressive Disorder: Lumateperone Study

We are testing lumateperone as an additional treatment for people with major depressive disorder who aren't responding well to their current antidepressants. The study will help us understand its effectiveness and safety.

Major Depressive Disorder≤3 monthsConfirmation phase (III)6-10 visitsInvestigational MedicinesCost ReimbursementPartially RemotePsychiatry

Endometrial Cancer: NEPA for Nausea Relief

We are studying whether a single dose of NEPA can effectively prevent nausea and vomiting in patients with endometrial cancer receiving chemotherapy. This trial also assesses the safety of NEPA and its effects on patients' quality of life.

Chemotherapy-Induced Nausea and Vomiting Prophylaxis≤3 monthsMonitoring phase (IV)No PlaceboInvestigational MedicinesInternal MedicineOncology

Heart Procedure: Protamine Administration Study

We are comparing routine versus selective use of protamine during transcatheter aortic valve implantation to see which method better reduces bleeding and death risks after the procedure.

Aortic Stenosis≤3 monthsConfirmation phase (III)Monitoring phase (IV)Standard MedicinesCardiologyInternal Medicine

Papulopustular Acne: Clindamycin/Tretinoin Gel Study

We are evaluating a new gel with Clindamycin and Tretinoin for treating papulopustular acne. The study compares its effects to an existing treatment and a placebo to see which works best.

Papulopustular Acne≤3 monthsConfirmation phase (III)6-10 visitsInvestigational MedicinesDermatology

Severe Brain Injury: Apomorphine Treatment Study

We are investigating whether apomorphine can help patients with disorders of consciousness. The study also aims to identify which patients may respond best to this treatment.

Severe Brain Injury and Disorder of Consciousness≤3 monthsEfficacy phase (II)11-15 visitsNo PlaceboStandard MedicinesPartially RemoteNeurology

Cytisine for Quitting Nicotine in E-Cigarettes and Tobacco

We are studying whether cytisine, combined with behavioral support, helps people quit using nicotine in e-cigarettes or tobacco cigarettes better than a placebo. This trial is for individuals motivated to stop using these products.

Quitting Electronic Cigarettes≤3 monthsConfirmation phase (III)Standard MedicinesPsychiatry

High Cardiovascular Risk: Rosuvastatin vs. Combination Therapy

We are studying whether high-intensity rosuvastatin or a combination of rosuvastatin and ezetimibe can effectively lower cholesterol in patients at high or very high risk for heart disease. The goal is to see if these treatments help achieve specific cholesterol targets.

High Cholesterol≤3 monthsConfirmation phase (III)Monitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesCardiologyInternal Medicine

UDCA for Visual Recovery After Retinal Detachment Surgery

We are studying whether UDCA can improve vision recovery in patients who have had surgery for retinal detachment. The trial also looks at the treatment's safety and other effectiveness measures.

Rhegmatogenous Retinal Detachment≤3 monthsConfirmation phase (III)Standard MedicinesOphthalmology

Cholestyramine for Obese Women: Pollutant Levels Study

We are exploring how cholestyramine treatment impacts harmful pollutant levels in obese women who may undergo bariatric surgery. This study aims to understand its effects before and after the surgery.

Epidermolysis Bullosa≤3 monthsEfficacy phase (II)No PlaceboStandard MedicinesDermatologyEndocrinologyInternal Medicine

IVF Luteal Phase Support: GnRH Agonist vs. hCG

We are studying whether a GnRH agonist can improve live birth rates and reduce miscarriages in women undergoing IVF compared to traditional hCG and progesterone support.

Assisted Reproductive Technology≤3 monthsConfirmation phase (III)No PlaceboStandard MedicinesGynecology and Obstetrics

Pyridoxine for Primary Sclerosing Cholangitis

We are studying whether pyridoxine can lower liver enzyme levels in people with primary sclerosing cholangitis. The trial will also look at its effects on vitamin B6 levels, liver function, and quality of life.

Primary Sclerosing Cholangitis≤3 monthsEfficacy phase (II)Standard MedicinesGastroenterologyHepatology

Perianal Crohn’s Disease: FAPi-PET Imaging Study

We are exploring whether a new imaging method can help visualize and measure healing in fistulas for patients with perianal Crohn’s disease. This study may also help predict how well treatments are working.

Crohn's DiseaseFistulizing Crohn's Disease≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesGastroenterologyInternal Medicine

Nutrition Timing After Major Abdominal Surgery

We are comparing early versus delayed nutrition support for patients recovering from major emergency abdominal surgery. The goal is to see which approach may lower the risk of infections after surgery.

Major Emergency Abdominal Surgery≤3 monthsMonitoring phase (IV)No PlaceboInvestigational MedicinesGastroenterology

Refractory Heart Failure: Dapagliflozin Study

We are investigating how Dapagliflozin may help patients with refractory heart failure eliminate sodium and manage fluid levels during peritoneal dialysis. This study aims to improve treatment options for these patients.

Refractory Heart Failure≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesCardiologyInternal MedicineNephrology