Search Clinical Trials in the European Union

Duration
Visits
Efficacy phase (II)
Intake methods
Benefits
Drugs
Locations
Clinical Specialty
1421-1440 of 1,738 trials

Alcohol Use Disorder: Sunobinop Study

We are testing whether Sunobinop can help reduce heavy drinking days for individuals with alcohol use disorder. This study aims to understand its effects on overall alcohol consumption and cravings.

Alcohol Use Disorder≤3 monthsEfficacy phase (II)Investigational MedicinesCost ReimbursementPsychiatry

Bladder Cancer: Intravesical Gemcitabine Treatment

We are studying the effectiveness and safety of a drug called gemcitabine for patients with low-grade bladder cancer. This trial aims to see how well it works in treating this specific type of cancer.

Bladder Cancer≤3 monthsEfficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesOncologyUrology

Heart Procedure: Comparing Blood Thinners

We are studying how two different blood-thinning treatments affect blood clotting in patients undergoing closure of heart defects. This may help us understand which treatment is safer and more effective after the procedure.

Patent Foramen Ovale (PFO) / Atrial Septum Defect (ASD)>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesCardiologyInternal Medicine

Rectal Cancer: Atezolizumab and Bevacizumab After Radiotherapy

We are studying a new treatment for low- to intermediate-risk rectal cancer to see if it helps prevent disease relapse and preserves organ function. The trial also evaluates the safety of this approach.

Colorectal Cancer>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesGastroenterologyOncology

Multiple Myeloma: ABBV-453 Treatment Study

We are studying the safety and effects of ABBV-453, alone or with other treatments, for adults with multiple myeloma. This research aims to understand how well it works and how it is tolerated by patients.

Multiple MyelomaSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteHematologyOncology

Advanced Solid Tumors: GSK5733584 with Anti-Cancer Therapies

We are studying a new drug, GSK5733584, combined with other cancer treatments for patients with advanced solid tumors. The trial aims to evaluate its safety and how well it may work in this setting.

Gynecological TumorsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesCost ReimbursementOncology

Sarcopenia Treatment: Nandrolone and Therapy

We are studying whether nandrolone, along with physiotherapy and diet, can improve muscle strength in people with sarcopenia. This research aims to find effective treatments for muscle loss.

Sarcopenia≤3 monthsEfficacy phase (II)Standard MedicinesCost ReimbursementInternal MedicineOrthopedics and Traumatology

Ovarian Cancer: Mirvetuximab Soravtansine Study

We are evaluating different dosing schedules of mirvetuximab soravtansine for patients with advanced ovarian, peritoneal, or fallopian tube cancers. This study aims to find the safest and most effective way to administer the treatment.

Advanced Ovarian and Fallopian Tube Cancer6-12 monthsEfficacy phase (II)11-15 visitsPost-Trial Drug AccessStandard MedicinesCost ReimbursementPartially RemoteGynecology and ObstetricsOncology

Advanced Ovarian Cancer: TORL-1-23 Treatment Study

We are studying the effectiveness of TORL-1-23 in women with advanced platinum-resistant ovarian cancer that expresses Claudin 6. This research aims to find new treatment options for this challenging condition.

Peritoneal CancerOvarian CancerFallopian Tube Cancer>2 yearsEfficacy phase (II)11-15 visitsPost-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementOncology

Ozone Treatment for Numbness from Chemotherapy

We are studying whether adding ozone therapy helps reduce numbness and tingling in patients with chemotherapy-induced nerve damage. The trial also looks at how this treatment affects overall quality of life and costs.

Chemotherapy-Induced Peripheral Neuropathy6-12 monthsEfficacy phase (II)Confirmation phase (III)>20 visitsStandard MedicinesInternal MedicineNeurologyOncology

Schizophrenia Treatment: Cannabidiol vs. Placebo

We are studying whether adding cannabidiol to standard antipsychotic treatment helps improve recovery in early schizophrenia. The trial will also look at safety and changes in mental and social functioning.

Remitted Schizophrenia1-2 yearsEfficacy phase (II)6-10 visitsInvestigational MedicinesPartially RemotePsychiatry

Advanced Lung Cancer: Atezolizumab vs. Atezolizumab Plus Bevacizumab

We are studying whether adding bevacizumab to atezolizumab helps patients with advanced non-small-cell lung cancer live longer than using atezolizumab alone. This trial is for those with high PD-L1 expression who have not yet received treatment.

Advanced Non-Small-Cell Lung Cancer1-2 yearsEfficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesOncology

Pembrolizumab for Advanced Adrenocortical Carcinoma

We are studying whether pembrolizumab can effectively treat advanced, progressive adrenocortical carcinoma. The trial also looks at its safety and how it affects patients' quality of life.

Adrenocortical Carcinoma6-12 monthsEfficacy phase (II)No PlaceboStandard MedicinesOncology

Alzheimer’s Disease: Dimethyl Fumarate Study

We are investigating whether dimethyl fumarate can improve memory and daily activities in patients with mild cognitive impairment and Alzheimer's disease. This study will also assess its effects on brain health and quality of life.

Alzheimer's Disease1-2 yearsEfficacy phase (II)Standard MedicinesNeurologyPsychiatry

MDS and CMML: PXS-5505 with 5-Azacitidine

We are studying a new treatment combining PXS-5505 and 5-Azacitidine for patients with MDS and CMML. The goal is to evaluate its safety and effectiveness compared to standard therapies.

Myelodysplastic Neoplasms and Chronic Myelomonocytic Leukemia>2 yearsSafety phase (I)Efficacy phase (II)HematologyOncology

SOD1 ALS: AMT-162 Gene Therapy

We are testing a new gene therapy for adults with SOD1 amyotrophic lateral sclerosis to see if it is safe and well-tolerated. We’re also exploring its potential effects on the disease.

Amyotrophic Lateral Sclerosis (ALS)>2 yearsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesPartially RemoteNeurology

Advanced Rare Cancers: Domvanalimab + Zimberelimab Study

We are investigating the safety and effectiveness of a new combination therapy for patients with advanced rare cancers that have not responded to previous treatments. This trial includes several types of rare cancers, aiming to find better treatment options.

Rare Cancers>2 yearsEfficacy phase (II)No PlaceboInvestigational MedicinesInternal MedicineOncology

Knee Osteoarthritis: KBP-336 Medication Study

We are testing a new medication for obese individuals with knee osteoarthritis to see if it helps reduce weight and pain. The study will also look at other symptoms and overall safety compared to a placebo.

Knee OsteoarthritisObesity6-12 monthsEfficacy phase (II)11-15 visitsInvestigational MedicinesPartially RemoteInternal MedicineOrthopedics and Traumatology

BOTOX® for Preventing Pancreatic Fistula After Surgery

We are studying whether BOTOX® injections before surgery can help prevent complications in patients undergoing distal pancreatectomy. This trial will assess the safety and effectiveness of this approach.

Postoperative Pancreatic Fistulas≤3 monthsSafety phase (I)Efficacy phase (II)Post-Trial Drug AccessNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteGastroenterologyInternal Medicine

Retinoblastoma: New Conservative Treatment Approaches

We are studying different chemotherapy and local treatment methods for children with retinoblastoma to see if they can preserve vision without using radiation. This trial includes various patient groups based on their specific conditions.

RetinoblastomaEfficacy phase (II)No PlaceboStandard MedicinesOncologyOphthalmology