Search Clinical Trials in the European Union

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141-160 of 552 trials

Ovarian Stimulation in Older Women: INOVEE Study

We are comparing two doses of a fertility medication to see which produces more healthy embryos in older women undergoing fertility treatment. This study aims to improve outcomes for women trying to conceive.

Female Infertility3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesEndocrinologyGynecology and Obstetrics

Pain Management in Laparoscopic Colorectal Surgery: Comparing Two Techniques

We are studying the effectiveness of two pain relief methods after laparoscopic colorectal surgery. Our goal is to find out which method reduces opioid use and improves recovery.

Patients Scheduled for Laparoscopic Colorectal Surgery1-2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesInternal MedicineOtolaryngology

Labor Induction: Outpatient vs. Inpatient Methods

We are studying whether inducing labor at home is as safe and effective as doing it in a hospital. We want to understand the costs and experiences of women and healthcare staff in both settings.

Induction of Labour3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesGynecology and Obstetrics

Genitourinary Syndrome of Menopause: Cellular Matrix Treatment

We are studying a new treatment combining platelet-rich plasma and hyaluronic acid for women with genitourinary syndrome of menopause. This trial compares its effects to a standard estrogen gel to see which works better for symptom relief.

Genitourinary Syndrome of Menopause3-6 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesGynecology and Obstetrics

Atrial Fibrillation: Amiodarone Treatment Study

We are studying whether a longer or shorter course of amiodarone helps people with persistent atrial fibrillation return to a normal heart rhythm before a procedure. This may improve outcomes for patients undergoing electrical cardioversion.

Atrial Fibrillation1-2 yearsMonitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesCardiology

Ulcerative Colitis: Adalimumab Treatment Comparison

We are comparing a new treatment approach with telemonitoring and education to standard care for patients starting adalimumab. The aim is to see if this helps manage ulcerative colitis more effectively.

Ulcerative Colitis>2 yearsMonitoring phase (IV)≤5 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesPartially RemoteGastroenterologyInternal Medicine

Pneumonia Prevention: 20-Valent Pneumococcal Vaccine

We are studying whether a new 20-valent pneumococcal vaccine helps prevent pneumonia in adults aged 65 and older. This trial will assess its effectiveness against specific types of pneumonia caused by certain bacteria.

Community Acquired Pneumonia>2 yearsMonitoring phase (IV)No PlaceboInvestigational MedicinesInfectious DiseasesPulmonology

COVID-19 Vaccine: Preventing Type 1 Diabetes in At-Risk Children

We are studying if vaccinating children with a higher genetic risk for type 1 diabetes against COVID-19 can lower their chances of developing diabetes and related autoimmune conditions. This research aims to see if the vaccine can help protect their health.

Risk for Type 1 Diabetes>2 yearsMonitoring phase (IV)11-15 visitsStandard MedicinesCost ReimbursementEndocrinologyInfectious Diseases

Pancreatic Cancer: Testing Enzyme Therapy

We are studying whether pancreatic enzyme replacement therapy can help patients with unresectable pancreatic cancer gain weight and improve their nutrition. This may enhance their quality of life and ability to handle chemotherapy.

Pancreatic Exocrine Insufficiency6-12 monthsMonitoring phase (IV)≤5 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesPartially RemoteGastroenterologyOncology

Low Back Pain: PRGF-Endoret® Treatment Study

We are investigating whether PRGF-Endoret® can effectively reduce pain and enhance quality of life in patients with chronic low back pain due to disc degeneration, compared to standard treatments.

Low Back PainMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesInternal MedicineOrthopedics and Traumatology

Chronic Kidney Disease: CKD-bioMatch Study

We are exploring whether a new treatment based on biomarkers can improve kidney function in patients with chronic kidney disease compared to standard care. This study aims to find better ways to manage CKD and its effects.

Chronic Kidney Disease>2 yearsMonitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesCost ReimbursementNephrology

Penile Rehabilitation After Prostate Cancer Surgery: PEHAB II

We are studying two approaches to help men regain erections after nerve-sparing prostate surgery. The goal is to see which method leads to better sexual function and quality of life.

Prostate Cancer>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesPartially RemoteUrology

Statin Intolerance: Personalized Treatment Study

We are exploring whether personalized treatment plans can help people who struggle with statin medications. The goal is to improve their cholesterol management while minimizing side effects.

High Cardiovascular RiskStatin Intolerance6-12 monthsMonitoring phase (IV)≤5 visitsInvestigational MedicinesCost ReimbursementPartially RemoteCardiologyInternal Medicine

Hip Replacement: PENG Block vs. Lumbar Plexus Block

We are comparing two anesthesia methods for hip replacement surgery to see which one provides better pain relief and helps patients recover faster. We're also looking at hospital stay length and any side effects.

Total Hip Replacement1-2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesOrthopedics and TraumatologyOtolaryngology

Vertebral Osteomyelitis: Early Oral Antibiotics Study

We are investigating if switching to oral antibiotics after one week is as effective as continuing intravenous treatment for pyogenic vertebral osteomyelitis. This study will also assess safety, hospital stays, and quality of life for patients.

Pyogenic Vertebral Osteomyelitis3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesInfectious DiseasesOrthopedics and TraumatologyRheumatology

Infectious Endocarditis: Shorter Antibiotic Treatment Study

We are investigating whether a shorter course of antibiotics is safe and effective for treating left-sided infectious endocarditis caused by specific bacteria. This study also looks at the potential cost benefits of this accelerated treatment.

Infectious Endocarditis≤3 monthsConfirmation phase (III)Monitoring phase (IV)No PlaceboInvestigational MedicinesCardiologyInfectious Diseases

Advanced Solid Tumors: Selpercatinib Access Program

We are providing access to selpercatinib for adults with locally advanced or metastatic solid tumors that have specific genetic changes. This program aims to help patients who may benefit from this targeted treatment.

Various Types of Cancer>2 yearsMonitoring phase (IV)Post-Trial Drug AccessNo PlaceboStandard MedicinesCost ReimbursementOncology

Rheumatoid Arthritis: MethMax Trial

We are studying how well methotrexate works for people with active rheumatoid arthritis. The goal is to see if it helps more patients reach remission or low disease activity compared to current treatments.

Rheumatoid Arthritis3-6 monthsMonitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesInternal MedicineRheumatology

Hemophilia A: Long-Term Follow-Up of BMN 270

We are investigating the long-term safety and effects of a gene therapy for severe hemophilia A in individuals who participated in a previous study. This includes looking at their quality of life and the need for additional treatments.

Hemophilia A>2 yearsMonitoring phase (IV)>20 visitsNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteHematology

Progesterone for Preventing Preterm Birth in Women with Placenta Previa

We are studying whether progesterone can help reduce the risk of preterm birth in women diagnosed with placenta previa. This trial will look at various outcomes, including the timing of birth and any side effects for mothers and babies.

Placenta Previa3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesGynecology and ObstetricsPediatrics