Search Clinical Trials in the European Union

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121-140 of 2,120 trials

Takotsubo Syndrome: New Treatment Approaches

We are studying whether a combination of adenosine and dipyridamole improves outcomes for patients with Takotsubo Syndrome. Additionally, we’re testing if apixaban can lower the risk of blood clots in these patients.

Takotsubo Syndrome>2 yearsMonitoring phase (IV)Standard MedicinesPartially RemoteCardiologyInternal Medicine

Generalized Myasthenia Gravis: Ravulizumab for Kids

We are studying the effects of Ravulizumab in children with Generalized Myasthenia Gravis to see how well it works and its safety. This trial will help us understand if it improves their quality of life.

Generalized Myasthenia Gravis3-6 monthsConfirmation phase (III)Post-Trial Drug AccessNo PlaceboStandard MedicinesPartially RemoteNeurologyPediatrics

Acute Ischemic Stroke: Redasemtide Study

We are investigating whether redasemtide can improve recovery in adults who have had an acute ischemic stroke. Participants will receive either the medication or a placebo to compare effects.

Ischaemic Stroke>2 yearsEfficacy phase (II)≤5 visitsInvestigational MedicinesCost ReimbursementPartially RemoteCardiologyNeurology

Prostate Cancer Imaging: PSMA-PET vs. mpMRI

We are comparing two imaging methods to see which better identifies critical areas in high-risk prostate cancer. This study may help improve diagnosis and treatment planning for patients.

Prostate Cancer>2 yearsConfirmation phase (III)No PlaceboStandard MedicinesOncologyUrology

Rituximab for Heart Attack Recovery

We are studying whether a single injection of rituximab can improve heart function in patients who have had a heart attack. This trial compares its effects to a placebo to see if it helps reduce heart damage.

ST Segment Elevation Myocardial InfarctionAcute Myocardial Infarction>2 yearsEfficacy phase (II)≤5 visitsStandard MedicinesPartially RemoteCardiologyInternal Medicine

Polymyalgia Rheumatica: Secukinumab Injection Study

We are studying whether secukinumab, combined with a glucocorticoid taper, can help patients with polymyalgia rheumatica achieve better remission compared to a placebo. This trial also looks at the safety and quality of life for participants.

Polymyalgia Rheumatica1-2 yearsConfirmation phase (III)16-20 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteInternal MedicineRheumatology

Ovarian Cancer: REGN5668 with Cemiplimab or REGN4018

We are studying the safety and effectiveness of REGN5668 when given with either Cemiplimab or REGN4018 for patients with ovarian cancer. This trial aims to find the best dose and see how well these combinations work.

Fallopian Tube CancerPrimary Peritoneal CancerOvarian CancerSafety phase (I)Efficacy phase (II)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteGynecology and ObstetricsOncology

Inclusion Body Myositis: ABC008 Treatment Study

We are studying the safety and effectiveness of a new treatment called ABC008 for people with Inclusion Body Myositis. The goal is to see if it improves muscle function and strength compared to a placebo.

Inclusion Body Myositis1-2 yearsEfficacy phase (II)Confirmation phase (III)>20 visitsPost-Trial Drug AccessStandard MedicinesPartially RemoteNeurologyRheumatology

Abdominal Aortic Aneurysm: Stem Cell Treatment Study

We are testing whether injecting stem cells into the aneurysm sac is safe and effective for patients undergoing endovascular repair. This study compares outcomes with those from traditional treatment methods.

Abdominal Aortic Aneurysm1-2 yearsEfficacy phase (II)No PlaceboInvestigational MedicinesCardiologyInternal MedicineOrthopedics and Traumatology

Roxadustat for Anemia in Children with Chronic Kidney Disease

We are studying a new treatment for anemia in children and adolescents with chronic kidney disease. The trial will evaluate its effectiveness, safety, and how it impacts daily life.

Nephrogenic Anemia1-2 yearsConfirmation phase (III)11-15 visitsNo PlaceboStandard MedicinesCost ReimbursementHematologyNephrology

Advanced Dedifferentiated Liposarcoma: Pemigatinib and Retifanlimab Study

We are studying the effects of two medications on patients with advanced dedifferentiated liposarcoma. The goal is to see if they improve treatment outcomes and quality of life.

Dedifferentiated Liposarcoma3-6 monthsEfficacy phase (II)No PlaceboStandard MedicinesOncology

Isolated MMA: Long-Term Study of mRNA-3705

We are evaluating the long-term safety and effects of mRNA-3705 in individuals with Isolated MMA who have participated in earlier studies. This research aims to understand how the treatment impacts health and daily activities over time.

Methylmalonic AciduriaSafety phase (I)Efficacy phase (II)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesPartially RemoteInternal Medicine

Kidney Transplant: Comparing rATG and Basiliximab

We are studying whether rATG is more effective than basiliximab in preventing kidney transplant rejection in sensitized patients without pre-existing antibodies. This trial aims to improve outcomes for kidney transplant recipients.

Kidney Transplant>2 yearsConfirmation phase (III)No PlaceboStandard MedicinesNephrology

Acute Myeloid Leukemia: Comparing Treatment Regimens

We are studying two different conditioning regimens for adults with acute myeloid leukemia before stem cell transplantation. The goal is to see which regimen may improve survival and recovery outcomes.

Acute Myeloid Leukemia in Remission>2 yearsConfirmation phase (III)6-10 visitsNo PlaceboStandard MedicinesHematology

Rheumatoid Arthritis: Precision Therapy Using Biomarkers

We are studying if tissue samples can help identify which RA patients will respond best to new biologic treatments. This may improve treatment outcomes for those who haven't benefited from standard therapies.

Rheumatoid ArthritisMonitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesRheumatology

Crohn's Disease: Risankizumab for Children

We are studying the safety and effectiveness of risankizumab in children aged 2 to under 18 with moderately to severely active Crohn's disease. This trial aims to help those who haven't responded to other treatments.

Crohn's Disease>2 yearsConfirmation phase (III)Post-Trial Drug AccessInvestigational MedicinesPartially RemoteGastroenterologyInternal Medicine

Nuwiq for Managing Bleeding in Hemophilia A Patients During Surgery

We are studying how well Nuwiq works alongside emicizumab for patients with severe hemophilia A undergoing major surgery. The goal is to see if it helps control bleeding effectively and safely.

Haemophilia AMonitoring phase (IV)No PlaceboStandard MedicinesHematology

Nuwiq for Women and Girls with Hemophilia A Needing Surgery

We are studying how well Nuwiq works to control bleeding during major surgery for women and girls with hemophilia A. The trial will also look at its safety and effects on blood product use.

Haemophilia A≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesHematologyInternal Medicine

Zilucoplan for Children with Generalized Myasthenia Gravis

We are studying the long-term safety of zilucoplan in children with generalized myasthenia gravis who participated in an earlier trial. This research aims to understand how well the treatment works and its effects over time.

Myasthenia GravisConfirmation phase (III)Post-Trial Drug AccessNo PlaceboStandard MedicinesPartially RemoteNeurologyPediatrics

Myasthenia Gravis: Rozanolixizumab for Kids

We are studying if rozanolixizumab is safe and effective for children with moderate to severe myasthenia gravis. This trial will help us understand how the medication works in young patients.

Myasthenia Gravis3-6 monthsEfficacy phase (II)Confirmation phase (III)No PlaceboStandard MedicinesNeurologyPediatrics