Search Clinical Trials in the European Union

≤3 months
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181-200 of 240 trials

Alcohol Use Disorder: Sunobinop Study

We are testing whether Sunobinop can help reduce heavy drinking days for individuals with alcohol use disorder. This study aims to understand its effects on overall alcohol consumption and cravings.

Alcohol Use Disorder≤3 monthsEfficacy phase (II)Investigational MedicinesCost ReimbursementPsychiatry

Bladder Cancer: Intravesical Gemcitabine Treatment

We are studying the effectiveness and safety of a drug called gemcitabine for patients with low-grade bladder cancer. This trial aims to see how well it works in treating this specific type of cancer.

Bladder Cancer≤3 monthsEfficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesOncologyUrology

Ulcerative Colitis: Encapsulated Stool Microbiome Study

We are investigating whether long-term treatment with encapsulated stool microbiome can improve symptoms in people with active ulcerative colitis. This study compares the treatment to a placebo to assess its effectiveness.

Active Ulcerative Colitis≤3 monthsConfirmation phase (III)Investigational MedicinesGastroenterologyInfectious Diseases

Bipolar Depression: Lithium vs. Cariprazine

We are comparing the effectiveness of lithium and cariprazine for treating acute depressive episodes in people with bipolar disorder. The goal is to find out which medication may lead to better improvements in mood.

Depressive Episode in Bipolar Disorder≤3 monthsMonitoring phase (IV)6-10 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemotePsychiatry

Sarcopenia Treatment: Nandrolone and Therapy

We are studying whether nandrolone, along with physiotherapy and diet, can improve muscle strength in people with sarcopenia. This research aims to find effective treatments for muscle loss.

Sarcopenia≤3 monthsEfficacy phase (II)Standard MedicinesCost ReimbursementInternal MedicineOrthopedics and Traumatology

BOTOX® for Preventing Pancreatic Fistula After Surgery

We are studying whether BOTOX® injections before surgery can help prevent complications in patients undergoing distal pancreatectomy. This trial will assess the safety and effectiveness of this approach.

Postoperative Pancreatic Fistulas≤3 monthsSafety phase (I)Efficacy phase (II)Post-Trial Drug AccessNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteGastroenterologyInternal Medicine

Congenital Nephrogenic Diabetes Insipidus: Fluconazole Study

We are testing whether fluconazole can help people with congenital nephrogenic diabetes insipidus reduce excessive urination and improve their quality of life. This study focuses on patients with a specific AVPR2 gene mutation.

Congenital Nephrogenic Diabetes Insipidus≤3 monthsEfficacy phase (II)≤5 visitsNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteNephrology

Opioid Use Disorder: Daridorexant Treatment

We are studying whether daridorexant can help reduce illicit substance use in people with opioid use disorder already on buprenorphine. The trial also looks at improvements in cravings, withdrawal symptoms, and overall treatment retention.

Opioid Use Disorder≤3 monthsEfficacy phase (II)11-15 visitsStandard MedicinesPsychiatry

Anesthesia Study: Ketamine vs. Propofol Combinations

We are comparing the effectiveness of ketamine alone and a ketamine-propofol mix against standard propofol for safe tracheal intubation in patients at risk of aspiration during surgery. The goal is to see which option leads to fewer complications and better tolerance.

Rapid Sequence Induction≤3 monthsConfirmation phase (III)No PlaceboStandard MedicinesInternal MedicineOtolaryngologyPsychiatry

Cisternal Lavage Therapy for Aneurysmal Subarachnoid Hemorrhage

We are studying a new treatment using Urokinase and Nimodipine for patients with aneurysmal subarachnoid hemorrhage. The aim is to see if this therapy improves brain function and is safe.

Aneurysmal Subarachnoid Hemorrhage≤3 monthsEfficacy phase (II)No PlaceboStandard MedicinesNeurology

Neurogenic Orthostatic Hypotension: Fludrocortisone Treatment

We are studying whether fludrocortisone can improve blood pressure and reduce symptoms in patients with neurogenic orthostatic hypotension. The trial will also assess the safety and quality of life for participants.

Neurogenic Orthostatic Hypotension≤3 monthsMonitoring phase (IV)Investigational MedicinesInternal MedicineNeurology

Knee Osteoarthritis: SYN321 Injection Study

We are testing a new injection for people with knee osteoarthritis to see if it is safe and effective. The study compares different doses of SYN321 to a placebo to assess its impact on symptoms.

Knee Osteoarthritis≤3 monthsSafety phase (I)Efficacy phase (II)Investigational MedicinesInternal MedicineOrthopedics and Traumatology

Alzheimer’s Disease: NTRX-07 Treatment Study

We are investigating the safety and tolerability of NTRX-07 in people with mild cognitive impairment or mild to moderate Alzheimer's disease. This study aims to understand how well the treatment works and its effects on patients.

Mild Cognitive Impairment (MCI)Mild to Moderate Alzheimer's Disease (AD)≤3 monthsEfficacy phase (II)≤5 visitsInvestigational MedicinesNeurology

Locally Advanced Rectal Cancer: FOLFOX Before Surgery

We are comparing the effects of chemotherapy before surgery to risk-adapted chemotherapy after surgery for patients with locally advanced rectal cancer. Our goal is to see which approach may lead to better disease-free survival and fewer complications.

Locally Advanced Rectal Cancer≤3 monthsConfirmation phase (III)No PlaceboStandard MedicinesOncology

Hidradenitis Suppurativa: IC0624 Treatment Study

We are testing a new medication, IC0624, for people with mild to moderate Hidradenitis Suppurativa. The study will help us understand its effects on symptoms, pain, and overall quality of life.

Hidradenitis Suppurativa≤3 monthsEfficacy phase (II)≤5 visitsInvestigational MedicinesDermatology

Ketamine Therapy for Obsessive-Compulsive Disorder

We are studying whether ketamine can effectively reduce symptoms of obsessive-compulsive disorder. This trial will help us understand its impact on mental function during stressful situations.

Obsessive Compulsive Disorder (OCD)≤3 monthsConfirmation phase (III)6-10 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesPartially RemotePsychiatry

Growth Hormone and Liver Fat Metabolism Study

We are investigating how growth hormone influences fat processing in the liver of healthy adults. Additionally, we will explore its effects in patients with acromegaly to understand fat secretion better.

AcromegalyHealthy Participants≤3 monthsEfficacy phase (II)No PlaceboStandard MedicinesEndocrinologyHepatology

Prolonged Grief Disorder: PEX010 Treatment

We are testing a new treatment called PEX010 for people experiencing prolonged grief disorder. The study aims to see if it can significantly reduce grief symptoms and explore the effects of self-touch.

Prolonged Grief Disorder≤3 monthsEfficacy phase (II)≤5 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemotePsychiatry

Type 2B von Willebrand Disease: BT200 Treatment Study

We are testing a new treatment called BT200 for people with Type 2B von Willebrand disease. The goal is to see if it improves blood clotting and is safe for use.

Von Willebrand's Disease Type 2B≤3 monthsEfficacy phase (II)11-15 visitsInvestigational MedicinesHematology

CBD for Alcohol Use Disorder: A Phase II Trial

We are studying whether adding cannabidiol to standard treatment helps patients with severe alcohol use disorder stay abstinent after inpatient care. The trial also looks at the safety of CBD and its effects on withdrawal and anxiety symptoms.

Alcohol Use Disorder≤3 monthsEfficacy phase (II)11-15 visitsInvestigational MedicinesInternal MedicinePsychiatry