Search Clinical Trials in the European Union

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321-340 of 552 trials

Pleural Empyema: Surgery vs. Drainage

We are studying whether surgery is more effective than drainage for treating pleural empyema. This trial will help us understand the best approach for patients with this condition.

Pleural Empyema>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesInternal MedicinePulmonology

Migraine Prevention: Comparing Common Medications

We are studying how well different medications prevent migraines in primary care patients. This trial aims to find out which treatment reduces migraine days and improves quality of life.

Migraine Headaches≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesInternal MedicineNeurology

Cytoreductive Surgery: HiPRESS Study

We are testing if low-dose argipressin can reduce fluid use and improve recovery during surgery for cancer treatment. This study compares it to standard treatment to see which is better for patients.

Disseminated Cancer≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesGastroenterologyInternal MedicineOrthopedics and Traumatology

Frozen Embryo Transfer: The Role of Corpus Luteum

We are studying how the presence of the corpus luteum affects pregnancies from frozen embryo transfers. This research may help us understand its impact on maternal and fetal health.

Infertility6-12 monthsMonitoring phase (IV)11-15 visitsNo PlaceboStandard MedicinesGynecology and Obstetrics

Postoperative Pain Relief: PENG Block for Hip Surgery

We are studying whether a nerve block can reduce pain after hip surgery called peri-acetabular osteotomy. This trial compares the nerve block to a placebo to see if it helps patients feel better and use fewer pain medications.

Periacetabular Osteotomy1-2 yearsMonitoring phase (IV)Standard MedicinesOrthopedics and TraumatologyOtolaryngology

Atrial Fibrillation: Dapagliflozin Treatment Study

We are investigating if dapagliflozin can help prevent the return of atrial fibrillation after cardioversion compared to usual care. This study aims to see how well it works in prolonging the time before atrial fibrillation recurs.

Atrial Fibrillation≤3 monthsConfirmation phase (III)Monitoring phase (IV)No PlaceboStandard MedicinesCardiologyInternal Medicine

Acute Myocarditis: Ibuprofen vs. Standard Pain Relief

We are studying whether ibuprofen can better improve heart health compared to regular pain relief in patients with acute myocarditis. This trial focuses on how these treatments affect heart imaging results after six months.

Acute Myocarditis>2 yearsMonitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesCardiologyInternal Medicine

Endurance Performance: Pseudoephedrine Study

We are investigating how a full dose of pseudoephedrine affects cycling performance in trained athletes after a tough race simulation. The study also looks at the right dosage and the body's response to it.

Healthy Volunteers6-12 monthsMonitoring phase (IV)Investigational MedicinesInternal MedicinePediatrics

Kidney Transplant Rejection: Everolimus Study

We are studying whether everolimus can help kidney transplant patients with a specific type of rejection maintain kidney function and reduce damage. This trial looks at its effects over six months.

Kidney Failure6-12 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesNephrology

Managing Anxiety in Gynecological Surgery: Hypnosis vs. Medication

We are studying whether hypnosis is more effective than traditional premedication in reducing anxiety for patients undergoing gynecological surgery.

Perioperative AnxietyMonitoring phase (IV)Gynecology and ObstetricsPsychiatry

Giant Cell Arteritis and Polymyalgia Rheumatica: Hydrocortisone Study

We are investigating whether hydrocortisone can help patients with GCA and PMR who report symptoms of adrenal insufficiency after stopping glucocorticoids. This study aims to provide better treatment options for these patients.

Tertiary Adrenal Insufficiency>2 yearsMonitoring phase (IV)≤5 visitsStandard MedicinesCost ReimbursementPartially RemoteEndocrinologyRheumatology

Preventing Constipation After Hip Surgery: Laxative Study

We are exploring which laxatives work best to prevent constipation in patients recovering from hip fracture surgery. This research aims to improve comfort and recovery after surgery.

Hip Fracture>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesGastroenterologyOrthopedics and Traumatology

Opioid Dependency Treatment: Suboxone vs. Methadone

We are comparing the effectiveness of Suboxone and methadone in reducing opioid misuse for patients with chronic pain. The study also looks at how these treatments affect pain relief, well-being, and cognitive function.

Opioid Use Disorder>2 yearsMonitoring phase (IV)≤5 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesCost ReimbursementInternal MedicinePsychiatry

Flu Vaccine Study: LAIV in Young Children

We are studying how the LAIV flu vaccine affects the immune response in young children. This research aims to see how well it protects against flu and influences overall health.

Influenza≤3 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPediatricsPulmonology

Relapsing-Remitting Multiple Sclerosis: Ozanimod Study

We are studying how ozanimod may help limit brain changes in people with relapsing-remitting multiple sclerosis. The trial looks at its effects on disease activity, cognition, fatigue, and quality of life.

Multiple Sclerosis>2 yearsMonitoring phase (IV)Neurology

HPV Infections: 2LPAPI® Treatment Study

We are testing a new treatment, 2LPAPI®, for people with high-risk HPV infections to see if it helps clear the virus better than a placebo. The study also looks at safety and how the treatment affects cervical cell health.

Human Papillomavirus Infection>2 yearsMonitoring phase (IV)≤5 visitsPost-Trial Drug AccessStandard MedicinesGynecology and ObstetricsInfectious Diseases

Influenza Vaccination: Antibody Responses Study

We are investigating how intranasal and intramuscular flu vaccines affect antibody levels in the nose. This research may help improve future vaccination methods.

Healthy Participants≤3 monthsMonitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteInfectious DiseasesPulmonology

Diabetic Macular Edema: Fluocinolone vs. Dexamethasone Implants

We are comparing two eye implants to see which one better improves vision and is more cost-effective for patients with resistant diabetic macular edema. This study also looks at how these treatments affect quality of life.

Diabetic Macular Oedema>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesCost ReimbursementOphthalmology

Ovarian Stimulation: Follitropin Delta and Dydrogesterone

We are studying a new ovarian stimulation method for egg donors to see if it produces similar results to traditional approaches. This research may help improve fertility treatments in the future.

Healthy Oocyte Donors1-2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesGynecology and Obstetrics

Craniotomy Pain Management: S-Ketamine Study

We are investigating whether adding s-ketamine to standard pain relief helps reduce opioid use and improve pain control after craniotomy in patients with drug-resistant epilepsy.

Post-Craniotomy Headache6-12 monthsMonitoring phase (IV)Standard MedicinesNeurologyOtolaryngologyPsychiatry