Search Clinical Trials in the European Union

Duration
Visits
Phase
Intake methods
Benefits
Drugs
Locations
Clinical Specialty
1721-1740 of 3,900 trials

Pamidronate for Pain in Sternocostoclavicular Hyperostosis

We are studying whether pamidronate can help reduce pain in patients with sternocostoclavicular hyperostosis. This trial will also look at improvements in daily activities and overall health.

Inflammation of the Sternal RegionSternocostoclavicular Hyperostosis1-2 yearsConfirmation phase (III)≤5 visitsPost-Trial Drug AccessStandard MedicinesOrthopedics and TraumatologyRheumatology

Acute Myeloid Leukemia: Multi-Peptide Vaccine Study

We are testing a new vaccine to see if it helps AML patients who are in complete remission after their first treatment. The goal is to improve their chances of staying in remission.

Acute Myeloid Leukemia>2 yearsSafety phase (I)HematologyOncology

Head and Neck Cancer: Petosemtamab Treatment Study

We are studying the effects of petosemtamab in patients with advanced head and neck cancer who have not responded to previous treatments. The goal is to see if it improves survival and tumor response compared to standard therapies.

Metastatic Head and Neck Squamous Cell Carcinoma>2 yearsConfirmation phase (III)11-15 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteOncology

Head and Neck Cancer: Petosemtamab with Pembrolizumab

We are studying a new treatment combination for patients with recurrent or metastatic head and neck cancer to see if it works better than standard treatment. This trial is for those with tumors that express PD-L1.

Metastatic Squamous Cell Carcinoma of the Head and Neck>2 yearsConfirmation phase (III)No PlaceboStandard MedicinesPartially RemoteOncology

Uveal Melanoma: Tebentafusp Treatment Study

We are studying whether the drug tebentafusp can help prevent cancer recurrence in patients with high-risk uveal melanoma after surgery or radiation. This trial also looks at the safety of the treatment compared to observation.

Uveal Melanoma6-12 monthsConfirmation phase (III)No PlaceboStandard MedicinesOncologyOphthalmology

Paroxysmal Nocturnal Hemoglobinuria: Pozelimab and Cemdisiran Therapy

We are studying the long-term safety and effectiveness of a combination therapy for adults with Paroxysmal Nocturnal Hemoglobinuria. This trial will help us understand its impact on symptoms like fatigue and hemoglobin levels.

Paroxysmal Nocturnal Hemoglobinuria>2 yearsConfirmation phase (III)11-15 visitsPost-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteHematologyInternal Medicine

Recurrent Herpes Labialis: Lipovir® Gel vs. Zovirax® Cream

We are studying whether Lipovir® Gel is as effective and tolerable as Zovirax® Cream for treating recurrent herpes labialis. Participants will also receive a placebo to help us understand the treatments better.

Cold Sores≤3 monthsConfirmation phase (III)Standard MedicinesDermatologyInfectious Diseases

Acne Vulgaris: N-Acetyl-GED-0507-34-Levo Gel

We are testing a new gel for people with acne vulgaris to see if it is safe and effective compared to a placebo. Participants will apply the gel once daily for the study.

Acne3-6 monthsConfirmation phase (III)≤5 visitsPost-Trial Drug AccessInvestigational MedicinesDermatology

Hypereosinophilic Syndrome: Depemokimab Study

We are investigating whether Depemokimab can help adults with Hypereosinophilic Syndrome manage their symptoms better than a placebo. This study aims to provide insights into its effectiveness and safety.

Hypereosinophilic Syndrome1-2 yearsConfirmation phase (III)Post-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteHematologyInternal Medicine

Myotonic Dystrophy Type 1: DYNE-101 Treatment Study

We are evaluating the safety and effects of a new treatment, DYNE-101, for people with Myotonic Dystrophy Type 1. The study aims to see how it impacts muscle health and overall well-being.

Myotonic Dystrophy>2 yearsSafety phase (I)Efficacy phase (II)16-20 visitsPost-Trial Drug AccessInvestigational MedicinesPartially RemoteNeurologyOrthopedics and Traumatology

Pneumococcal Vaccine Response: Age and HIV Impact

We are studying how age and HIV infection affect the immune response to pneumococcal vaccination. This research aims to improve vaccine effectiveness for different populations.

HIV Infection6-12 monthsConfirmation phase (III)Monitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesCost ReimbursementInfectious DiseasesInternal Medicine

Pancreatic, Lung, Breast, and Colorectal Cancers: [177Lu]Lu-NNS309

We are evaluating a new treatment for patients with pancreatic, lung, breast, and colorectal cancers. The study aims to assess its safety and how well it works in these cancer types.

Non-Small Cell Lung Cancer (NSCLC)Pancreatic Ductal Adenocarcinoma (PDAC)Colorectal Cancer (CRC)>2 yearsSafety phase (I)Oncology

Carvedilol vs. Flecainide for Ventricular Arrhythmias

We are comparing two medications to see which one better reduces abnormal heartbeats in people with idiopathic ventricular arrhythmias. The study also looks at how these treatments affect quality of life and any side effects.

Ventricular ExtrasystolesMonomorphic Ventricular TachycardiaIdiopathic Ventricular Arrhythmias6-12 monthsMonitoring phase (IV)No PlaceboStandard MedicinesCardiology

Type 1 Diabetes: LY3938577 Study

We are assessing a new medication to see how safe it is and how it works in people with type 1 diabetes and healthy participants. This study may help us understand its potential benefits for managing diabetes.

Type 1 Diabetes6-12 monthsSafety phase (I)DiabetologyEndocrinology

Mixed Dyslipidemia: RBD5044 Treatment Study

We are testing a new medication, RBD5044, for people with mixed dyslipidemia to see if it improves cholesterol and lipid levels. The study also looks at the safety of this treatment when given as injections.

Mixed Dyslipidemia6-12 monthsEfficacy phase (II)≤5 visitsInvestigational MedicinesCardiologyInternal Medicine

Cystic Fibrosis: Anakinra Treatment Study

We are testing the safety and effectiveness of anakinra for adults and possibly adolescents with cystic fibrosis. The study aims to see if it improves lung function and quality of life.

Cystic Fibrosis>2 yearsEfficacy phase (II)Standard MedicinesInternal MedicinePulmonology

Severe Diffuse Cutaneous Systemic Sclerosis: Rapcabtagene Autoleucel vs. Rituximab

We are studying a new treatment to see if it works better than rituximab for people with severe diffuse cutaneous systemic sclerosis. The trial will also evaluate the safety of this new therapy.

Systemic Scleroderma1-2 yearsEfficacy phase (II)6-10 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteInternal MedicineRheumatology

Tranexamic Acid for Postoperative Complications in Plastic Surgery

We are studying whether applying tranexamic acid to surgical wounds can reduce re-bleeding and other complications after plastic surgery. This trial includes both men and women over 18 years old.

Healthy Participants Undergoing SurgeryMonitoring phase (IV)No PlaceboStandard MedicinesHematologyOrthopedics and Traumatology

Metformin for Prolonging Pregnancy in Preterm Preeclampsia

We are studying whether metformin can help extend pregnancy by at least 5 days in individuals with preterm preeclampsia. Additionally, we aim to see if it improves health outcomes for mothers and their babies.

Pre-eclampsiaHELLP SyndromeHypertensive Disorders of Pregnancy>2 yearsConfirmation phase (III)Investigational MedicinesGynecology and ObstetricsInternal Medicine

Multiple Myeloma: Teclistamab with Lenalidomide

We are studying a new treatment combining teclistamab and lenalidomide for patients with newly diagnosed multiple myeloma after stem cell transplant. The aim is to see if this combination works better than lenalidomide alone in maintaining remission.

Newly Diagnosed Multiple MyelomaConfirmation phase (III)Post-Trial Drug AccessNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteHematologyOncology