Search Clinical Trials in the European Union

≤3 months
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161-180 of 240 trials

Chronic Spontaneous Urticaria and Hidradenitis Suppurativa: INF904 Study

We are evaluating the safety of an oral medication called INF904 for people with moderate to severe chronic spontaneous urticaria or hidradenitis suppurativa. This study will help us understand how the medication works in the body.

Chronic Spontaneous UrticariaHidradenitis Suppurativa≤3 monthsEfficacy phase (II)6-10 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteAllergologyDermatology

Medulloblastoma Treatment: MEMMAT Trial

We are studying a combination of anti-cancer drugs for children with recurrent brain tumors. The goal is to see if this treatment improves response rates and overall survival.

Rare CNS Tumors≤3 monthsEfficacy phase (II)No PlaceboInvestigational MedicinesNeurologyOncology

Optic Pathway Glioma: CHF6467 Eye Drops

We are studying the safety and effectiveness of a new eye drop treatment for children and young adults with optic pathway gliomas. This trial aims to see if it can improve their vision.

Optic Glioma≤3 monthsSafety phase (I)Efficacy phase (II)Post-Trial Drug AccessInvestigational MedicinesNeurologyOphthalmology

Clindamycin for Infections: Impact of Rifampicin and Obesity

We are studying how body weight and the antibiotic rifampicin affect the effectiveness of clindamycin in treating infections. This research may help improve treatment strategies for patients with varying body types.

Hidradenitis SuppurativaProsthetic Joint InfectionsFracture Related Infections≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesCost ReimbursementInfectious DiseasesInternal Medicine

Post-Surgical Hypoparathyroidism: Indapamide Treatment

We are studying whether daily Indapamide can help manage calcium levels in patients with post-surgical hypoparathyroidism. This trial will also look at the safety of the treatment and its effects on urinary calcium excretion.

Hypoparathyroidism≤3 monthsMonitoring phase (IV)6-10 visitsStandard MedicinesCost ReimbursementEndocrinologyInternal Medicine

Serotonin and Decision-Making: A Behavioral Study

We are investigating how serotonin influences learning and decision-making in individuals. The study also looks at how personal traits like perfectionism and impulsivity relate to these behaviors.

Healthy Participants≤3 monthsMonitoring phase (IV)≤5 visitsStandard MedicinesPsychiatry

Pediatric Hepatic Tumor Trial: Evaluating Treatments for Hepatoblastoma and Hepatocellular Carcinoma

We are studying different treatment approaches for children with liver tumors to see which may improve outcomes and reduce side effects. This trial also aims to collect samples for future research on these cancers.

Liver Cancer (Hepatoblastoma and Hepatocellular Carcinoma)≤3 monthsConfirmation phase (III)No PlaceboStandard MedicinesHepatologyOncology

ANCA-Vasculitis: Corticosteroid Dosing Study

We are investigating if taking corticosteroids twice daily helps patients with ANCA-vasculitis maintain better blood sugar levels. This study will measure glucose control using continuous monitoring.

ANCA-associated VasculitisRapid-Progressive Glomerulonephritis≤3 monthsConfirmation phase (III)Monitoring phase (IV)≤5 visitsNo PlaceboStandard MedicinesEndocrinologyRheumatology

Pancreatic Cancer: Sotorasib with Chemotherapy

We are studying the safety of combining sotorasib with standard chemotherapy for patients with advanced pancreatic cancer that has a specific genetic mutation. This trial aims to see if this combination improves treatment outcomes.

Pancreatic Cancer≤3 monthsSafety phase (I)No PlaceboStandard MedicinesGastroenterologyOncology

Iron Deficiency Anemia in Children: Ferumoxytol Study

We are testing the safety and effectiveness of the drug ferumoxytol for children with iron deficiency anemia. This study compares it to an existing treatment to see how well it works.

Iron Deficiency Anemia≤3 monthsConfirmation phase (III)≤5 visitsNo PlaceboInvestigational MedicinesHematologyPediatrics

Prucalopride for Refractory Gastro-Esophageal Reflux Disease

We are testing a new medication for patients with GERD who still have symptoms despite taking standard treatments. The goal is to see if this drug can improve their reflux symptoms.

Gastro-esophageal Reflux Disease (GERD)≤3 monthsMonitoring phase (IV)≤5 visitsPost-Trial Drug AccessStandard MedicinesCost ReimbursementPartially RemoteGastroenterologyInternal Medicine

Chronic Urticaria: Testing Remibrutinib

We are exploring whether remibrutinib can help adults with Chronic Urticaria manage their symptoms better than a placebo. The study also looks at the safety of this new treatment and its effects on quality of life.

Chronic Urticaria≤3 monthsEfficacy phase (II)≤5 visitsInvestigational MedicinesPartially RemoteAllergologyDermatology

Genital Herpes: IM-250 Treatment Study

We are investigating a new medication, IM-250, for people with recurrent genital herpes to see if it can help reduce outbreaks. The study will also look at the safety of this treatment when given weekly.

Genital Herpes≤3 monthsSafety phase (I)Efficacy phase (II)≤5 visitsInvestigational MedicinesCost ReimbursementDermatologyInfectious Diseases

Clebopride for the Treatment of Rumination Syndrome

We are studying whether clebopride can improve symptoms in people suspected of having rumination syndrome. The trial compares its effects to a placebo to see how well it works.

Rumination Syndrome≤3 monthsMonitoring phase (IV)≤5 visitsInvestigational MedicinesCost ReimbursementPartially RemoteGastroenterology

Buspirone for Weak Esophageal Motility

We are studying whether buspirone can improve swallowing and esophageal function in patients with poor motility. This trial compares the effects of buspirone to a placebo on symptoms and esophageal pressure measurements.

Ineffective Motility or Absent Peristalsis≤3 monthsMonitoring phase (IV)6-10 visitsStandard MedicinesPartially RemoteGastroenterology

Generalized Anxiety Disorder: ITI-1284 Treatment Study

We are evaluating the safety and effectiveness of a new medication, ITI-1284, for people with Generalized Anxiety Disorder who haven't found relief with current treatments. This study compares ITI-1284 to a placebo to see how well it works.

Generalized Anxiety Disorder≤3 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesPsychiatry

Sjögren's Syndrome: Stem Cell Treatment for Dry Mouth

We are studying whether injecting stem cells into the salivary glands can improve saliva flow in patients with dry mouth from Sjögren's syndrome. This trial will also assess safety and other effects on saliva quality.

Sjögren's Syndrome≤3 monthsSafety phase (I)Efficacy phase (II)≤5 visitsInvestigational MedicinesOrthopedics and TraumatologyRheumatology

Baricitinib for Children Hospitalized with COVID-19

We are studying how the medication baricitinib works in children aged 1 to under 18 years who are hospitalized with COVID-19. This research aims to ensure the safety and proper dosing for young patients.

COVID-19≤3 monthsConfirmation phase (III)6-10 visitsNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteInfectious DiseasesPulmonology

Patent Ductus Arteriosus: Paracetamol Treatment in Premature Infants

We are studying whether early treatment with Paracetamol helps extremely low birth weight infants with Patent Ductus Arteriosus avoid serious complications. This trial compares the effects of Paracetamol to a placebo.

Patent Ductus Arteriosus≤3 monthsConfirmation phase (III)Investigational MedicinesCardiologyPediatrics

Delayed Sleep-Wake Phase Disorder: Tasimelteon Study

We are investigating whether tasimelteon can help people with Delayed Sleep-Wake Phase Disorder fall asleep faster and improve their overall sleep quality compared to a placebo.

Delayed Sleep-Wake Phase Disorder≤3 monthsConfirmation phase (III)≤5 visitsStandard MedicinesPartially RemoteNeurologyPsychiatry